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  1. Article

    Open Access

    Research, education, ethics consultation: evaluating a Bioethics Unit in an Oncological Research Hospital

    This study aims to quantitatively and qualitatively evaluate the activities of a Bioethics Unit (BU) 5 years since its implementation (2016–2020). The BU is a research unit providing empirical research on ethi...

    Ludovica De Panfilis, Morten Magelssen, Massimo Costantini in BMC Medical Ethics (2022)

  2. Article

    Open Access

    Effectiveness of a nurse-delivered (FOCUS+) and a web-based (iFOCUS) psychoeducational intervention for people with advanced cancer and their family caregivers (DIAdIC): study protocol for an international randomized controlled trial

    Worldwide, millions of people with advanced cancer and their family caregivers are experiencing physical and psychological distress. Psychosocial support and education can reduce distress and prevent avoidable...

    Orphé Matthys, Aline De Vleminck, Sigrid Dierickx, Luc Deliens in BMC Palliative Care (2021)

  3. Article

    Open Access

    Providing dignity therapy to patients with advanced cancer: a feasibility study within the setting of a hospital palliative care unit

    Dignity is a basic principle of palliative care and is intrinsic in the daily practice of professionals assisting individuals with incurable diseases. Dignity Therapy (DT) is a short-term intervention aimed at...

    Francesca Nunziante, Silvia Tanzi, Sara Alquati, Cristina Autelitano in BMC Palliative Care (2021)

  4. Article

    Open Access

    “Teach for ethics in palliative care”: a mixed-method evaluation of a medical ethics training programme

    Training in medical ethics aims to educate health care professionals in dealing with daily care ethical issues. To guarantee quality of life and spiritual and emotional support, palliative care professionals h...

    Ludovica De Panfilis, Silvia Tanzi, Marta Perin, Elena Turola in BMC Palliative Care (2020)

  5. Article

    Open Access

    Early palliative care versus standard care in haematologic cancer patients at their last active treatment: study protocol of a feasibility trial

    Patients with advanced haematological malignancies suffer from a very high symptom burden and psychological, spiritual, social and physical symptoms comparable with patients with metastatic non-haematological ...

    Silvia Tanzi, Stefano Luminari, Silvio Cavuto, Elena Turola in BMC Palliative Care (2020)

  6. Article

    Open Access

    Glia-to-neuron transfer of miRNAs via extracellular vesicles: a new mechanism underlying inflammation-induced synaptic alterations

    Recent evidence indicates synaptic dysfunction as an early mechanism affected in neuroinflammatory diseases, such as multiple sclerosis, which are characterized by chronic microglia activation. However, the mo...

    Ilaria Prada, Martina Gabrielli, Elena Turola, Alessia Iorio in Acta Neuropathologica (2018)

  7. Article

    Open Access

    Microenvironment inflammatory infiltrate drives growth speed and outcome of hepatocellular carcinoma: a prospective clinical study

    In HCC, tumor microenvironment, heavily influenced by the underlying chronic liver disease, etiology and stage of the tissue damage, affects tumor progression and determines the high heterogeneity of the tumor...

    Rosina Critelli, Fabiola Milosa, Francesca Faillaci in Cell Death & Disease (2017)

  8. Article

    Open Access

    Effect of extracellular vesicles derived from distinct brain cells on Aβ toxicity and assembly: focus on Microglia derived vesicles

    Pooja Joshi, Elena Turola, Ana Ruiz, Alessandra Bergami, Dacia Libera in SpringerPlus (2015)

  9. No Access

    Article

    Bone Marrow Mesenchymal Stromal Cells Drive Protective M2 Microglia Polarization After Brain Trauma

    Microglia/macrophages (M) are major contributors to postinjury inflammation, but they may also promote brain repair in response to specific environmental signals that drive classic (M1) or alternative (M2) pol...

    Elisa R. Zanier, Francesca Pischiutta, Loredana Riganti in Neurotherapeutics (2014)