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Article
The increasing role of cardiac magnetic resonance to evaluate cardiotoxicity of platinum-based chemotherapy: lessons learnt from asymptomatic germ cell cancer survivors
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Article
The role of intraoperative neuromonitoring in preventing lesions of the spinal accessory nerve during functional neck dissection
Intraoperative neuromonitoring (IONM) in thyroid surgery offers a valid aid to the operator in identifying the recurrent laryngeal nerve and preserving its function. Recently, IONM has also been used in other ...
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Article
Open AccessmiRNome profiling of lung cancer metastases revealed a key role for miRNA-PD-L1 axis in the modulation of chemotherapy response
Locally advanced non-small cell lung cancer (NSCLC) is frequent at diagnosis and requires multimodal treatment approaches. Neoadjuvant chemotherapy (NACT) followed by surgery is the treatment of choice for ope...
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Article
Open AccessA new minimally invasive technique for the repair of diastasis recti: a pilot study
Diastasis recti is an abdominal wall defect that occurs frequently in women during pregnancy. Patients with diastasis can experience lower back pain, uro-gynecological symptoms, and discomfort at the level of ...
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Article
Therapeutic Efficacy of a Coriolus versicolor-Based Vaginal Gel in Women with Cervical Uterine High-Risk HPV Infection: A Retrospective Observational Study
A Coriolus versicolor-based vaginal gel is available for treating women with cervical uterine high-risk human papillomavirus (HPV) infection through re-epithelizing and re-balancing microbiota actions.
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Chapter
Renal Vessels
In this chapter we illustrate the different imaging techniques available for the study of renal vessels, with particular reference to advantages and limitations of each technique and to selection criteria acco...
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Article
Effect of iodinated contrast medium on thyroid function: a study in children undergoing cardiac computed tomography
Few studies, and with conflicting results, have evaluated the potential effects of iodinated contrast media on children’s thyroid function.
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Article
Median nerve evaluation by shear wave elastosonography: impact of “bone-proximity” hardening artifacts and inter-observer agreement
Peripheral nerves frequently travel close to the bone surface and are, therefore, prone to elastosonographic “bone-proximity” hardening artifacts. The impact of these artifacts on quantitative measurements of ...
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Article
Radiological exams on end-stage oncologic patients before hospice admission
To evaluate frequency, type, and cost of diagnostic and interventional radiological exams performed on end-stage oncologic patients in the 90 days before Hospice admission.
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Article
Open AccessLung Cancer Onset in Wild Type Mice Following Bone Marrow Reconstitution with krasv12 Cells
A role for bone-marrow-derived cells (BMDCs) in tissue repair and malignancy onset has been proposed, but their contribution is still debated. We tested the ability of BMDCs containing the inducible krasV12 oncog...
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Article
Open AccessPAT-ChIP coupled with laser microdissection allows the study of chromatin in selected cell populations from paraffin-embedded patient samples
The recent introduction of pathology tissue-chromatin immunoprecipitation (PAT-ChIP), a technique allowing chromatin immunoprecipitation from formalin-fixed and paraffin-embedded (FFPE) tissues, has expanded t...
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Article
MR-guided stereotactic breast biopsy using a mixed ferromagnetic-nonmagnetic coaxial system with 12- to 18-gauge needles: clinical experience and long-term outcome
This study investigated the clinical application of a magnetic-resonance (MR)-guided breast biopsy (MRBB) system consisting of a nonmagnetic coaxial needle and a ferromagnetic core biopsy needle.
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Chapter
Peripheral Vessels
Magnetic resonance angiography (MRA) has become a fundamental imaging modality in the assessment of peripheral arterial disease. Three-dimensional contrast-enhanced MRA (3D CE-MRA) provides a luminographic stu...
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Chapter
Cardiomiopatie
Le cardiomiopatie (CMP) costituiscono un eterogeneo gruppo di patologie associate a disfunzione cardiaca, secondo la definizione fornita dalla Task Force della WHO-ISFC nel 1995 [1]. Le cardiomiopatie sono state ...
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Article
FISH analysis of hematological neoplasias with 1p36 rearrangements allows the definition of a cluster of 2.5 Mb included in the minimal region deleted in 1p36 deletion syndrome
Rearrangements in the distal region of the short arm of chromosome 1 are recurrent aberrations in a broad spectrum of human neoplasias. However, neither the location of the breakpoints (BP) on 1p36 nor the can...
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Article
Molecular characterization of a t(1;3)(p36;q21) in a patient with MDS. MEL1 is widely expressed in normal tissues, including bone marrow, and it is not overexpressed in the t(1;3) cells
Patients with myeloid malignancies and either the 3q21q26 syndrome or t(1;3)(p36;q21) have been reported to share similar clinicopathological features and a common molecular mechanism for leukemogenesis. Overe...
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Article
A homeobox gene, HLXB9, is the major locus for dominantly inherited sacral agenesis
Partial absence of the sacrum is a rare congenital defect which also occurs as an autosomal dominant trait; association with anterior meningocoele, presacral teratoma and anorectal abnormalities constitutes th...
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Article
Cytogenetic rearrangements involving the loss of the Sonic Hedgehog gene at 7q36 cause holoprosencephaly
Holoprosencephaly (HPE) is a genetically heterogeneous disorder that affects the midline development of the forebrain and midface in humans. As a step toward identifying one of the HPE genes, we have set out to ...
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Article
Mutations in the human Sonic Hedgehog gene cause holoprosencephaly
Holoprosencephaly (HPE) is a common developmental defect of the forebrain and frequently the midface in humans, with both genetic and environmental causes. HPE has a prevalence of 1:250 during embryogenesis an...
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Article
Search for mutations in pancreatic sufficient cystic fibrosis Italian patients: detection of 90% of molecular defects and identification of three novel mutations
A cohort of 31 cystic fibrosis patients showing pancreatic sufficiency and bearing an unidentified mutation on at least one chromosome was analyzed through denaturing gradient gel electrophoresis of the whole ...