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Article
Open AccessPreviously reported CCDC26 risk variant and novel germline variants in GALNT13, AR, and MYO10 associated with familial glioma in Finland
Predisposing factors underlying familial aggregation of non-syndromic gliomas are still to be uncovered. Whole-exome sequencing was performed in four Finnish families with brain tumors to identify rare predisp...
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Article
Open AccessIntegrative proteomics in prostate cancer uncovers robustness against genomic and transcriptomic aberrations during disease progression
To understand functional consequences of genetic and transcriptional aberrations in prostate cancer, the proteomic changes during disease formation and progression need to be revealed. Here we report high-thro...
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Article
Open AccessSegmentum: a tool for copy number analysis of cancer genomes
Somatic alterations, including loss of heterozygosity, can affect the expression of oncogenes and tumor suppressor genes. Whole genome sequencing enables detailed characterization of such aberrations. However,...
