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  1. Article

    Role of MKK3–p38 MAPK signalling in the development of type 2 diabetes and renal injury in obese db/db mice

    Obesity and diabetes are associated with increased intracellular p38 mitogen-activated protein kinase (MAPK) signalling, which may promote tissue inflammation and injury. Activation of p38 MAPK can be induced ...

    A. K. H. Lim, D. J. Nikolic-Paterson, F. Y. Ma, E. Ozols, M. C. Thomas… in Diabetologia (2009)

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  2. Article

    Monocyte chemoattractant protein-1-induced tissue inflammation is critical for the development of renal injury but not type 2 diabetes in obese db/db mice

    Tissue macrophage accumulation is thought to induce insulin resistance during obesity and stimulate the progression of diabetic nephropathy. Monocyte chemoattractant protein-1 (MCP-1) is a potent stimulator of...

    F. Y. Chow, D. J. Nikolic-Paterson, F. Y. Ma, E. Ozols, B. J. Rollins… in Diabetologia (2007)

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