-
Chapter
Human Allergogeneticists Should Listen to Their Dog’s Barking
A colony of Beagle dogs was used within the last 6 years to develop an allergie dog model. The dogs were sensitized to various allergens, such as recombinant Betvi (birch) and Phi p5 (timothy), ovalbumin, pean...
-
Chapter
Low Molecular Weight Cytokine Inducers
Skin is in many ways a unique immunological organ acting as a primary interface between the host and the outside environment. It provides an important barrier function against intruding antigens and an efficie...
-
Article
Accelerated platelet reconstitution following transplantation of bone marrow cells derived from IL-6-treated donor mice
We transplanted bone marrow cells derived from normal donor mice treated with IL-6 to study the effect on the hematopoietic recovery of lethally irradiated (8.5 Gy) recipients. Male Balb/C mice were treated f...
-
Article
Prediction of the role of granulocyte-macrophage colony-stimulating factor in animals and man from in vitro results
The possibility of predicting the clinical effects of cytokines from in vitro data is discussed, using GM-CSF as an example. GM-CSF incubated with bone marrow cells has been shown to induce proliferation and c...
-
Article
IL-2, IL-3, and IFN-gamma differently affect in vivo frequencies of circulating precursors of cytotoxic T lymphocytes (CTL-p)
Experimental animal and human in vivo studies have previously demonstrated the impact of exogenous administration of various cytokines on frequencies of circulating myeloid and LAK precursor cells. For the fir...
-
Article
Immunotherapy in sepsis
-
Chapter and Conference Paper
In Vivo Synergism of Interleukin-3 and Interleukin-6 on Thrombopoiesis in Primates
A substantial amount of information suggests that the process of platelet production is regulated by distinct factors acting at different levels of cellular development [1]. Several cytokines have been shown t...
-
Chapter and Conference Paper
The In Vivo Effects of IL-3 and GM-CSF in Primates
Hemopoietic growth factors are glycoprotein hormones which regulate the growth, differentiation, and function of hemopoietic cells [1]. Interleukin-3 (IL-3) and granulocyte-macrophage colony-stimulating factor...
-
Chapter and Conference Paper
Expression of Interleukin Receptors on Human Eosinophils, Basophils, and Mast Cells
Inflammatory cells involved in allergic reactions such as basophils, eosinophils or mast cells are derived from hemopoietic stem cells. Recently, hemopoietic growth factors have been shown to promote different...
-
Article
Entrapment of animal cells for production of monoclonal antibodies and other biomolecules
Animal cell technology is attracting considerable interest because of the capacity of animal cell cultures to synthesize or transform complex compounds such as virus vaccines, immunochemicals, hormones or enzymes
-
Article
Killer T cell responces to influenza a during a drift period: Studies in mice
After intravenous immunization of mice with any influenza A H3N2 drift strain attempts to restimulation of cytotoxic T cell (CTL) activities with the same virus or other drift period variants were unsuccessful...
