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Open AccessAdvancements in the fabrication and characterization of actinide targets for superheavy element production
The heaviest elements can exclusively be produced in actinide-target based nuclear fusion reactions with intense heavy-ion beams. Ever more powerful accelerators deliver beams of continuously increasing intens...
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Article
Prognostic factors and follow-up parameters in patients with paroxysmal nocturnal hemoglobinuria (PNH): experience of the Austrian PNH network
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare hematologic disease characterized by a deregulated complement system, chronic Coombs-negative, intravascular hemolysis, and a variable clinical course with s...
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Open AccessChronic myelomonocytic leukemia patients with RAS pathway mutations show high in vitro myeloid colony formation in the absence of exogenous growth factors
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Article
Selected spectroscopic results on element 115 decay chains
Thirty correlated α-decay chains were observed in an experiment studying the fusion-evaporation reaction 48Ca + 243Am at the GSI Helmholtzzentrum für Schwerionenforschung. The decay characteristics of the majori...
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Preparation of actinide targets for the synthesis of the heaviest elements
The heaviest elements are synthesized in heavy-ion induced hot fusion reactions with various actinide targets. Because the actinide material is often available only in very limited amounts, a deposition method...
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High intensity target wheel at TASCA: target wheel control system and target monitoring
At GSI Darmstadt, the gas-filled recoil separator transactinide separator and chemistry apparatus (TASCA) is in operation for experiments with superheavy elements. It is optimized for hot-fusion reactions with...
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Article
Zervikale, inguinale und abdominelle Lymphknotendissektion
Chirurgische Lymphknoten (LK)-Dissektionen können unter diagnostischer Zielsetzung als „Servicechirurgie“ angesehen werden. Die Eingriffe dienen der Differenzialdiagnose einer LK-Pathologie und zum Tumor-Stagi...
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Open AccessA randomised multicentre phase II study with cisplatin/docetaxel vs oxaliplatin/docetaxel as first-line therapy in patients with advanced or metastatic non-small cell lung cancer
This study was designed to compare cisplatin/docetaxel with oxaliplatin/docetaxel in patients with advanced and metastatic non-small lung cancer as a first-line treatment.
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Open AccessFeasibility of perioperative chemotherapy with infusional 5-FU, leucovorin, and oxaliplatin with (FLOT) or without (FLO) docetaxel in elderly patients with locally advanced esophagogastric cancer
The aim of this exploratory subgroup analysis of the fluorouracil, oxaliplatin, docetaxel (FLOT)65+ trial was to determine tolerability and feasibility of perioperative chemotherapy in elderly, potentially ope...
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Article
Wasserkraft in Österreich — aktueller Bestand und Decision Support System (DSS WASSERKRAFT)
Die Rolle der Wasserkraft in Österreich ist derzeit von einer zunehmend politischen, wirtschaftlichen und gesellschaftlichen Diskussion geprägt. Das Aufeinandertreffen verschiedener Interessen, wie zum Beispie...
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Article
Open AccessAnthracycline rechallenge using pegylated liposomal doxorubicin in patients with metastatic breast cancer: a pooled analysis using individual data from four prospective trials
The aim of this study was to determine the activity of anthracycline rechallenge using pegylated liposomal doxorubicin (PLD) in patients with metastatic breast cancer (MBC) previously treated with conventional...
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Article
Efficacy and safety of sorafenib in patients with advanced renal cell carcinoma with and without prior cytokine therapy, a subanalysis of TARGET
Before the development of targeted therapies, administration of cytokines (e.g., interleukin-2, interferon-α) was the primary systemic treatment option for advanced renal cell carcinoma. Sorafenib, an oral tar...
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Article
Neue Ansätze im integrierten Hochwassermanagement: Floodplain Evaluation Matrix FEM, flussmorphologischer Raumbedarf FMRB und räumlich differenziertes Vegetationsmanagement egetationsmanagement VeMaFLOOD
This paper presents three new approaches within the integrated flood management, which have been developed or optimized in FloodRisk II. (I) The Floodplain Evaluation Matrix (FEM) allows an objective evaluatio...
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Article
WT1 peptide-specific T cells generated from peripheral blood of healthy donors: possible implications for adoptive immunotherapy after allogeneic stem cell transplantation
The Wilms tumor antigen, WT1, is expressed at high levels in various types of leukemia and solid tumors, including lung, breast, colon cancer and soft tissue sarcomas. The WT1 protein has been found to be high...
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Article
Konditionierung von Ischämie/Reperfusion-Phänomenen
Rekonstruktionen im thorakoabdominalen Abschnitt der Aorta ziehen mehr oder weniger akzentuierte Ischämie/Reperfusion-Sequenzen nach sich. Deren Folgen sind bestenfalls eine vorübergehende Funktionsstörung des...
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Article
Open AccessValproic acid (VPA) in patients with refractory advanced cancer: a dose escalating phase I clinical trial
Altered histone deacetylase (HDAC) activity has been identified in several types of cancer. This study was designed to determine the safety and maximum tolerated dose (MTD) of valproic acid (VPA) as an HDAC in...
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FCKW Rückbau Entsorgungsstrategie der noch in Verwendung befindlichen Ozon abbauenden Stoffe in Dämmstoffen des Bauwesens
Nach der derzeit geltenden Gesetzeslage in Österreich sind alle FCKW geschäumten Dämmstoffe des Bauwesens nach ihrem Gebrauch als gefährliche Abfälle einzustufen. In Österreich war im Jahr 2003 in den XPS- und...
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Open AccessLUD00-014: Phase I Study of recombinant vaccinia-NY-ESO-1 (rV-NY-ESO-1) and recombinant fowlpox-NY-ESO-1 (rF-NY-ESO-1) in patients with NY-ESO-1 or LAGE positive cancers
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Article
Synchronous bilateral endoscopic adrenalectomy: experiences after 18 operations
Background: Patients who undergo unilateral adrenalectomy are known to benefit from the endoscopic procedure. Only a few reports on bilateral endoscopic adrenalectomy exist. The optimal a...
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Article
On the decay properties of 269Hs and indications for the new nuclide 270Hs
In bombardments of 248Cm with 143.7-146.8 MeV 26Mg ions the nuclides 269Hs and presumably 270Hs were produced. After chemical isolation, Hs atoms were identified by observing genetically linked nuclear-decay chai...