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  1. Article

    Open Access

    Screening for PTSD and TBI in Veterans using Routine Clinical Laboratory Blood Tests

    Post-traumatic stress disorder (PTSD) is a mental disorder diagnosed by clinical interviews, self-report measures and neuropsychological testing. Traumatic brain injury (TBI) can have neuropsychiatric symptoms...

    Mu Xu, Ziqiang Lin, Carole E. Siegel, Eugene M. Laska in Translational Psychiatry (2023)

  2. Article

    Correction: A DNA methylation clock associated with age-related illnesses and mortality is accelerated in men with combat PTSD

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    Ruoting Yang, Gwyneth W. Y. Wu, Josine E. Verhoeven, Aarti Gautam in Molecular Psychiatry (2021)

  3. Article

    Open Access

    Pre-deployment risk factors for PTSD in active-duty personnel deployed to Afghanistan: a machine-learning approach for analyzing multivariate predictors

    Active-duty Army personnel can be exposed to traumatic warzone events and are at increased risk for develo** post-traumatic stress disorder (PTSD) compared with the general population. PTSD is associated wit...

    Katharina Schultebraucks, Meng Qian, Duna Abu-Amara, Kelsey Dean in Molecular Psychiatry (2021)

  4. No Access

    Article

    A DNA methylation clock associated with age-related illnesses and mortality is accelerated in men with combat PTSD

    DNA methylation patterns at specific cytosine-phosphate-guanine (CpG) sites predictably change with age and can be used to derive “epigenetic age”, an indicator of biological age, as opposed to merely chronolo...

    Ruoting Yang, Gwyneth W. Y. Wu, Josine E. Verhoeven, Aarti Gautam in Molecular Psychiatry (2021)

  5. Article

    Open Access

    Epigenetic biotypes of post-traumatic stress disorder in war-zone exposed veteran and active duty males

    Post-traumatic stress disorder (PTSD) is a heterogeneous condition evidenced by the absence of objective physiological measurements applicable to all who meet the criteria for the disorder as well as divergent...

    Ruoting Yang, Aarti Gautam, Derese Getnet, Bernie J. Daigle in Molecular Psychiatry (2021)

  6. No Access

    Article

    Neural correlates of anger expression in patients with PTSD

    Anger is a common and debilitating symptom of post-traumatic stress disorder (PTSD). Although studies have identified brain circuits underlying anger experience and expression in healthy individuals, how these...

    Neir Eshel, Adi Maron-Katz, Wei Wu, Duna Abu-Amara in Neuropsychopharmacology (2021)

  7. Article

    Open Access

    Utilization of machine learning for identifying symptom severity military-related PTSD subtypes and their biological correlates

    We sought to find clinical subtypes of posttraumatic stress disorder (PTSD) in veterans 6–10 years post-trauma exposure based on current symptom assessments and to examine whether blood biomarkers could differ...

    Carole E. Siegel, Eugene M. Laska, Ziqiang Lin, Mu Xu in Translational Psychiatry (2021)

  8. Article

    Open Access

    Multi-omic biomarker identification and validation for diagnosing warzone-related post-traumatic stress disorder

    Post-traumatic stress disorder (PTSD) impacts many veterans and active duty soldiers, but diagnosis can be problematic due to biases in self-disclosure of symptoms, stigma within military populations, and limi...

    Kelsey R. Dean, Rasha Hammamieh, Synthia H. Mellon, Duna Abu-Amara in Molecular Psychiatry (2020)

  9. Article

    Open Access

    Polygenic risk associated with post-traumatic stress disorder onset and severity

    Post-traumatic stress disorder (PTSD) is a psychiatric illness with a highly polygenic architecture without large effect-size common single-nucleotide polymorphisms (SNPs). Thus, to capture a substantial porti...

    Burook Misganaw, Guia Guffanti, Adriana Lori, Duna Abu-Amara in Translational Psychiatry (2019)

  10. No Access

    Article

    Posttraumatic stress disorder, symptoms, and white matter abnormalities among combat-exposed veterans

    Posttraumatic stress disorder (PTSD) is associated with abnormalities in functional connectivity of a specific cortico-limbic network; however, less is known about white matter abnormalities providing structur...

    Kirstin Aschbacher, Synthia H. Mellon, Owen M. Wolkowitz in Brain Imaging and Behavior (2018)