7 Result(s)
within
Drishya Kurup
Biomedicine, general
Infectious Diseases
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Article
Open AccessEffects of adjuvants in a rabies-vectored Ebola virus vaccine on protection from surrogate challenge
Ebola virus is the primary contributor to the global threat of filovirus severe hemorrhagic fever, and Ebola virus disease has a case fatality rate of 50–90%. An inactivated, bivalent filovirus/rabies virus va...
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Article
Open AccessInactivated rabies-vectored SARS-CoV-2 vaccine provides long-term immune response unaffected by vector immunity
The objective of this study is to further analyze recombinant rabies virus-vectored SARS-CoV-2 vaccine, CORAVAX, as an effective COVID-19 vaccine strategy. CORAVAX has proven immunogenic and protective against...
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Article
Open AccessMeasles-based Zika vaccine induces long-term immunity and requires NS1 antibodies to protect the female reproductive tract
Zika virus (ZIKV) can cause devastating effects in the unborn fetus of pregnant women. To develop a candidate vaccine that can protect human fetuses, we generated a panel of live measles vaccine (MV) vectors e...
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Article
Open AccessA single dose of replication-competent VSV-vectored vaccine expressing SARS-CoV-2 S1 protects against virus replication in a hamster model of severe COVID-19
The development of effective countermeasures against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent responsible for the COVID-19 pandemic, is a priority. We designed and produced ConVa...
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Article
Open AccessRabies virus-based COVID-19 vaccine CORAVAX™ induces high levels of neutralizing antibodies against SARS-CoV-2
The recently emerged coronavirus SARS-CoV-2, the causative agent of COVID-19, is rapidly spreading in the world. The exponentially expanding threat of SARS-CoV-2 to global health highlights the urgent need for...
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Article
Open AccessPublisher Correction: Rabies-based vaccine induces potent immune responses against Nipah virus
In the original published version of this Article, the figure legends were attached to the wrong figures. The legend for Fig. 2 was moved to Fig. 4, the legend for Fig. 3 was moved to Fig. 2, and the legend fo...
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Article
Open AccessRabies-based vaccine induces potent immune responses against Nipah virus
Nipah Virus (NiV) is a re-emerging zoonotic pathogen in the genus Henipavirus of the Paramyxoviridae family of viruses. NiV is endemic to Bangladesh and Malaysia and is highly fatal to both livestock and humans (...
