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  1. Article

    Open Access

    A single immunization with a modified vaccinia Ankara vectored vaccine producing Sudan virus-like particles protects from lethal infection

    A new vectored vaccine MVA-VLP-SUDV was generated against Sudan ebolavirus (SUDV) combining the advantages of the immunogenicity of a live attenuated vaccine vector (Modified Vaccinia Ankara, MVA) with the aut...

    Delphine C. Malherbe, Arban Domi, Mary J. Hauser, Caroline Atyeo… in npj Vaccines (2022)

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  2. Article

    Open Access

    Differential V2-directed antibody responses in non-human primates infected with SHIVs or immunized with diverse HIV vaccines

    V2p and V2i antibodies (Abs) that are specific for epitopes in the V1V2 region of the HIV gp120 envelope (Env) do not effectively neutralize HIV but mediate Fc-dependent anti-viral activities that have been co...

    Svenja Weiss, Vincenza Itri, Ruimin Pan, Xunqing Jiang… in Nature Communications (2022)

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  3. Article

    Open Access

    A single dose of replication-competent VSV-vectored vaccine expressing SARS-CoV-2 S1 protects against virus replication in a hamster model of severe COVID-19

    The development of effective countermeasures against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent responsible for the COVID-19 pandemic, is a priority. We designed and produced ConVa...

    Delphine C. Malherbe, Drishya Kurup, Christoph Wirblich, Adam J. Ronk… in npj Vaccines (2021)

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  4. Article

    Open Access

    Modified vaccinia Ankara vaccine expressing Marburg virus-like particles protects guinea pigs from lethal Marburg virus infection

    We introduce a new vaccine platform against Marburg virus (MARV) combining the advantages of the immunogenicity of a highly attenuated vaccine vector (Modified Vaccinia Ankara, MVA) with the authentic conforma...

    Delphine C. Malherbe, Arban Domi, Mary J. Hauser, Michelle Meyer… in npj Vaccines (2020)

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  5. Article

    Open Access

    Single-dose bNAb cocktail or abbreviated ART post-exposure regimens achieve tight SHIV control without adaptive immunity

    Vertical transmission accounts for most human immunodeficiency virus (HIV) infection in children, and treatments for newborns are needed to abrogate infection or limit disease progression. We showed previously...

    Mariya B. Shapiro, Tracy Cheever, Delphine C. Malherbe… in Nature Communications (2020)

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  6. No Access

    Article

    17. Mainzer Allergie-Workshop

    Martina Thiel, Oliver Drews, Heidrun Behrendt, Angelika Görg… in Allergo Journal (2005)