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Article
Open AccessChemoradiotherapy versus surgery after neoadjuvant chemoimmunotherapy in patients with stage III NSCLC: a real-world multicenter retrospective study
The optimal treatment after neoadjuvant chemoimmunotherapy for patients with stage III non-small cell lung cancer (NSCLC) is unclear. This study aimed at comparing the efficacy and safety of chemoradiotherapy ...
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Article
Open AccessSYVN1-mediated ubiquitylation directs localization of MCT4 in the plasma membrane to promote the progression of lung adenocarcinoma
Tumour cells mainly generate energy from glycolysis, which is commonly coupled with lactate production even under normoxic conditions. As a critical lactate transporter, monocarboxylate transporter 4 (MCT4) is...
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Article
Open AccessPrognostic significance of 4R lymph node dissection in patients with right primary non-small cell lung cancer
To investigate the prognostic significance of station 4R lymph node (LN) dissection in patients who underwent operations for right primary non-small cell lung cancer (NSCLC).
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Article
TPP1 OB-fold domain protein suppresses cell proliferation and induces cell apoptosis by inhibiting telomerase recruitment to telomeres in human lung cancer cells
Maintaining telomeres by recruiting telomerase-to-chromosome ends is essential for cancer cell survival. Inhibiting telomerase recruitment to telomeres represents a novel strategy for telomere-based lung cance...
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Article
Open AccessSurvival analysis of patients with non-small cell lung cancer who underwent surgical resection following 4 lung cancer resection guidelines
To compare survival of patients with non-small cell lung cancer (NSCLC) who underwent surgical resection and lymph node sampling based on guidelines proposed by the American College of Surgeons Oncology Group ...
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Article
Open AccessHedgehog/Gli promotes epithelial-mesenchymal transition in lung squamous cell carcinomas
Squamous cell carcinomas (SCC) account for approximately 30% of non-small cell lung cancer. Investigation of the mechanism of invasion and metastasis of lung SCC will be of great help for the development of me...
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Article
Open AccessSMO expression level correlates with overall survival in patients with malignant pleural mesothelioma
Malignant mesothelioma is an aggressive, treatment-resistant tumor arising from mesothelium of pleura, peritoneum and pericardium. Despite current combined regimen, its prognosis remains dismal, calling for mo...
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Article
Expression of FAK and PTEN in Bronchioloalveolar Carcinoma and Lung Adenocarcinoma
Bronchioloalveolar carcinoma (BAC) is classified as a subset of lung adenocarcinoma but has a distinct clinical presentation, tumor biology, response to therapy, and prognosis compared with other subtypes of l...
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Article
Clinical characteristics and prognostic analysis of 107 patients with bronchioloalveolar carcinoma
OBJECTIVE To study the clinical characteristics and prognostic factors for bronchioloalveolar carcinoma.
