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  1. No Access

    Article

    The hepatotoxicity of Polygonum multiflorum: The emerging role of the immune-mediated liver injury

    Herbal and dietary supplements (HDS)-induced liver injury has been a great concern all over the world. Polygonum multiflorum Thunb., a well-known Chinese herbal medicine, is recently drawn increasing attention be...

    Tai Rao, Ya-ting Liu, **ang-chang Zeng, Chao-peng Li… in Acta Pharmacologica Sinica (2021)

  2. No Access

    Article

    Quantification of Meranzin Hydrate in Rat Hippocampus and Plasma by LC–MS/MS: A Compound Derived from Chaihu–Shugan–San Displays Antidepressant Potential

    Meranzin hydrate (MH), a compound derived from Chaihu–Shugan–San (CSS), displayed potent preclinical antidepressant functions. In this study, an LC–MS/MS method was developed and validated to quantify the MH i...

    ** Huang, Yi**g He, Weihua Huang, Zhirong Tan, **gbo Peng… in Chromatographia (2015)

  3. Article

    Pharmacokinetic interactions between ilaprazole and clarithromycin following ilaprazole, clarithromycin and amoxicillin triple therapy

    To investigate the drug interactions between ilaprazole, a new proton pump inhibitor, and clarithromycin following ilaprazole, clarithromycin and amoxicillin combination therapy.

    Shan Cao, Gan Zhou, Dong-sheng Ou-YANG, Hui-zi Wu, Kui **ao… in Acta Pharmacologica Sinica (2012)

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  4. Article

    Lack of effect of genetic polymorphisms of SLCO1B1 on the lipid-lowering response to pitavastatin in Chinese patients

    To investigate the SLCO1B1 388A>G and 521T>C polymorphisms in hyperlipidemia patients and evaluate the effect of the two polymorphisms on the lipid-lowering efficacy of pitavastatin.

    Guo-** Yang, Hong Yuan, Bin Tang, Wei Zhang… in Acta Pharmacologica Sinica (2010)

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  5. Article

    An improved LC-MS/MS method for quantitative determination of ilaprazole and its metabolites in human plasma and its application to a pharmacokinetic study

    To improve and validate an analytical method based on liquid chromatography and electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) for the quantitative measurement of ilaprazole and its two metabl...

    Gan Zhou, Zhi-rong Tan, Wei Zhang, Dong-sheng Ou-Yang… in Acta Pharmacologica Sinica (2009)

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  6. No Access

    Article

    Validated LC–MS–MS Method for Quantitative Determination of Batifiban in Human Plasma and Its Application to a Pharmacokinetic Study

    Batifiban is a new platelet GPIIb/IIIa receptor antagonist. In this work, an analytical method based on liquid chromatography and electrospray ionization tandem mass spectrometry has been firstly developed and...

    Zhi-Rong Tan, Dong-Sheng Ou-Yang, Gan Zhou, Yao Chen, Wei-Yong Li… in Chromatographia (2009)

  7. Article

    Distributive characteristics of Ser49Gly and Gly389Arg genetic polymorphisms of β1-adrenoceptor in Chinese Han and Dai populations

    Genetic polymorphisms causing Ser49Gly and Gly389Arg mutants of β1- adrenoceptor may result in significant changes in the function of this receptor. The aim of the present study was to investigate the frequencies...

    Zhao-qian Liu, Jie Liu, Zhi-hua **ang, Min-yu Hu, Wei Mo… in Acta Pharmacologica Sinica (2006)

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