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  1. No Access

    Article

    Dual-Region Computed Tomography Radiomics-Based Machine Learning Predicts Subcarinal Lymph Node Metastasis in Patients with Non-small Cell Lung Cancer

    Noninvasively and accurately predicting subcarinal lymph node metastasis (SLNM) for patients with non-small cell lung cancer (NSCLC) remains challenging. This study was designed to develop and validate a tumor...

    Hao-Ji Yan MD, Jia-Sheng Zhao MD, Hou-Dong Zuo MD, PhD in Annals of Surgical Oncology (2024)

  2. Article

    Open Access

    Genome-wide analysis of MYB transcription factor family and AsMYB1R subfamily contribution to ROS homeostasis regulation in Avena sativa under PEG-induced drought stress

    The myeloblastosis (MYB) transcription factor (TF) family is one of the largest and most important TF families in plants, playing an important role in a life cycle and abiotic stress.

    Yang Chen, Aixue Li, ** Yun, Quan Chen, Dayu Pan, Rui Guo, Han Zhang in BMC Plant Biology (2024)

  3. Article

    Open Access

    ATP6V0A1-dependent cholesterol absorption in colorectal cancer cells triggers immunosuppressive signaling to inactivate memory CD8+ T cells

    Obesity shapes anti-tumor immunity through lipid metabolism; however, the mechanisms underlying how colorectal cancer (CRC) cells utilize lipids to suppress anti-tumor immunity remain unclear. Here, we show th...

    Tu-**ong Huang, Hui-Si Huang, Shao-Wei Dong, Jia-Yan Chen in Nature Communications (2024)

  4. Article

    Open Access

    Neuroimaging and natural language processing-based classification of suicidal thoughts in major depressive disorder

    Suicide is a growing public health problem around the world. The most important risk factor for suicide is underlying psychiatric illness, especially depression. Detailed classification of suicide in patients ...

    Dong Yun Lee, Gihwan Byeon, Narae Kim, Sang Joon Son in Translational Psychiatry (2024)

  5. Article

    Open Access

    SETDB1 regulates short interspersed nuclear elements and chromatin loop organization in mouse neural precursor cells

    Transposable elements play a critical role in maintaining genome architecture during neurodevelopment. Short Interspersed Nuclear Elements (SINEs), a major subtype of transposable elements, are known to harbor...

    Dai**g Sun, Yueyan Zhu, Wenzhu Peng, Shenghui Zheng, Jie Weng in Genome Biology (2024)

  6. Article

    Open Access

    NBS1 lactylation is required for efficient DNA repair and chemotherapy resistance

    The Warburg effect is a hallmark of cancer that refers to the preference of cancer cells to metabolize glucose anaerobically rather than aerobically1,2. This results in substantial accumulation of lacate, the end...

    Hengxing Chen, Yun Li, Huafu Li, **ancong Chen, Huafeng Fu, Deli Mao, Wei Chen in Nature (2024)

  7. No Access

    Article

    Salvage haploidentical transplantation for graft failure after first haploidentical allogeneic stem cell transplantation: an updated experience

    Graft failure is a fatal complication following allogeneic stem cell transplantation where a second transplantation is usually required for salvage. However, there are no recommended regimens for second transp...

    Rui Ma, Dan-** Zhu, **ao-Hui Zhang, Lan-** Xu, Yu Wang in Bone Marrow Transplantation (2024)

  8. Article

    Open Access

    Comparison of digital and analog [68Ga]Ga-PSMA-11 PET/CT for detecting post-prostatectomy biochemical recurrence in prostate cancer patients: a prospective study

    Digital positron emission tomography/computed tomography (PET/CT) has shown enhanced sensitivity and spatial resolution compared with analog PET/CT. The present study compared the diagnostic performance of dig...

    Yong-il Kim, Dong Yun Lee, Changhwan Sung, Sang Ju Lee, Seung Jun Oh in Scientific Reports (2024)

  9. No Access

    Article

    Advancements and Challenges in the Carbon Fiber-Reinforced Polymer (CFRP) Trimming Process

    In this review, we comprehensively examine the carbon fiber-reinforced polymer (CFRP) trimming process, covering both conventional machining techniques and novel approaches. We explore various methods, includi...

    Jaewoo Seo, Dong Chan Kim, Hyunmin Park in International Journal of Precision Enginee… (2024)

  10. No Access

    Article

    Containing Nitrogen and Phosphorus Porous Organic Polymer-Supported Rhodium Catalyst for Hydroformylation of Olefins

    Hydroformylation of olefins with CO and H2 is an attractive approach to synthesize value-added aldehydes. Numerous efforts have been dedicated to the development of novel and efficient catalyst systems, given the...

    Yongcheng Lan, Dong Yun, Chungu **a, Bo Qian, Jianhua Liu in Catalysis Letters (2024)

  11. No Access

    Article

    Far-Infrared Therapy Based on Graphene Ameliorates High-Fat Diet-Induced Anxiety-Like Behavior in Obese Mice via Alleviating Intestinal Barrier Damage and Neuroinflammation

    The consumption of a high-fat diet (HFD) has been implicated in the etiology of obesity and various neuropsychiatric disturbances, including anxiety and depression. Compelling evidence suggests that far-infrar...

    **-shui Zhang, Shuo Li, **n Cheng, **ao-cui Tan, Yu-long Huang in Neurochemical Research (2024)

  12. No Access

    Article

    Coagulation engineering of surfactant-based wet spinning of carbon nanotube fibers

    One of the key challenges for the commercialization of carbon nanotube fibers (CNTFs) is their large-scale economic production. Among CNTF spinning methods, surfactant-based wet spinning is one of the promisin...

    Yun Ho Jeong, Jaegyun Im, Dong-Myeong Lee, Min Chan Kim, Daehan Oh in Carbon Letters (2024)

  13. No Access

    Article

    Toward a solid microneedle patch for rapid and enhanced local analgesic action

    Analgesic creams find widespread application as adjuncts for localized anesthesia prior to surgical procedures. Nevertheless, the onset of analgesic action is protracted due to the skin barrier’s inherent char...

    Yue Liu, Ze Qiang Zhao, Ling Liang, Li Yue **g in Drug Delivery and Translational Research (2024)

  14. No Access

    Article

    Exogenous melatonin enhanced cadmium stress tolerance of cucumber seedlings (Cucumis sativus L.)

    Cadmium (Cd) stress seriously affects cucumber growth, yield, and quality. Melatonin (MT) can enhance plant resistance to abiotic stresses. However, studies on the mechanism of MT in enhancing plant resistance...

    **n Kang, Zi-Qi Pei, Ting-Ting Xu, Cui-Yun Dong, Xue Bai, Cheng Ma, Qiao Zhu in Biologia (2024)

  15. Article

    Improvement in corrosion resistance of Mg97Zn1Y2 alloy by Zr addition

    Magnesium alloys, known for their exceptional lightweight properties, have presented challenges in various applications due to their limited corrosion resistance. In this study, the corrosion resistance of Mg97Zn

    Di-qing Wan, Yu-meng Sun, Yan-dan Xue, Shao-yun Dong, Guo-liang Han in China Foundry (2024)

  16. Article

    Open Access

    SARS-CoV-2 antigenemia and RNAemia in association with disease severity in patients with COVID-19

    Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for COVID-19, causes a spectrum of symptoms ranging from mild upper to severe lower respiratory tract infections. However, the d...

    Dong-Min Kim, Merlin Jayalal Lawrence Panchali, Choon-Mee Kim in Scientific Reports (2024)

  17. Article

    Open Access

    Molecular genomic and epigenomic characteristics related to aspirin and clopidogrel resistance

    Mediators, genomic and epigenomic characteristics involving in metabolism of arachidonic acid by cyclooxygenase (COX) and lipoxygenase (ALOX) and hepatic activation of clopidogrel have been individually sugges...

    Jei Kim, Byoung-Soo Shin, Dae-Hyun Kim, Dong-Ick Shin in BMC Medical Genomics (2024)

  18. No Access

    Article

    Glial growth factor 2 treatment alleviates ischemia and reperfusion-damaged integrity of the blood-brain barrier through decreasing Mfsd2a/caveolin-1-mediated transcellular and Pdlim5/YAP/TAZ-mediated paracellular permeability

    The impairment of blood-brain barrier (BBB) integrity is the pathological basis of hemorrhage transformation and vasogenic edema following thrombolysis and endovascular therapy. There is no approved drug in th...

    **ao-ling Zhang, Wei-hong Du, Shu-xia Qian, Xu-dong Lu in Acta Pharmacologica Sinica (2024)

  19. Article

    Open Access

    Noninvasive prediction of lymph node metastasis in pancreatic cancer using an ultrasound-based clinicoradiomics machine learning model

    This study was designed to explore and validate the value of different machine learning models based on ultrasound image-omics features in the preoperative diagnosis of lymph node metastasis in pancreatic canc...

    Dong-yue Wen, Jia-min Chen, Zhi-** Tang, **-shu Pang in BioMedical Engineering OnLine (2024)

  20. No Access

    Article

    Mendelian randomization evidence for the causal effect of mental well-being on healthy aging

    Mental well-being relates to multitudinous lifestyle behaviours and morbidities and underpins healthy aging. Thus far, causal evidence on whether and in what pattern mental well-being impacts healthy aging and...

    Chao-Jie Ye, Dong Liu, Ming-Ling Chen, Li-Jie Kong, Chun Dou in Nature Human Behaviour (2024)

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