3 Result(s)

Article

Sooty mangabey genome sequence provides insight into AIDS resistance in a natural SIV host

Whole-genome sequencing and comparative genomic analysis of immune-related genes of Cercocebus atys and Macaca mulatta identify candidate genes, such as ICAM2 and TLR4, that may explain the AIDS resistance of C. ...

David Palesch, Steven E. Bosinger, Gregory K. Tharp, Thomas H. Vanderford… in Nature (2018)

Article

Toward an AIDS vaccine: lessons from natural simian immunodeficiency virus infections of African nonhuman primate hosts

The design of an effective AIDS vaccine has eluded the efforts of the scientific community to the point that alternative approaches to classic vaccine formulations have to be considered. We propose here that H...

Donald L Sodora, Jonathan S Allan, Cristian Apetrei, Jason M Brenchley… in Nature Medicine (2009)

Article

Nef-mediated TCR-CD3 and MHC-I down-modulation prevents CD4+ T cell depletion in natural SIV infection

Michael Schindler, Jan Münch, Olaf Kutsch, Hui Li, Mario L Santiago… in Retrovirology (2006)