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  1. Article

    Open Access

    Mechanical regulation of nucleocytoplasmic translocation in mesenchymal stem cells: characterization and methods for investigation

    Mesenchymal stem cells (MSCs) have immune-modulatory and tissue-regenerative properties that make them a suitable and promising tool for cell-based therapy application. Since the bio-chemo-mechanical environme...

    Lucia Boeri, Diego Albani, Manuela Teresa Raimondi… in Biophysical Reviews (2019)

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  2. No Access

    Article

    Hot Genes in Schizophrenia: How Clinical Datasets Could Help to Refine their Role

    We investigated the effect of a set of SNPs within 5 genes identified by GWASs as possible risk genes for schizophrenia (SCZ) in two independent samples, comprising 176 SCZ patients and 326 controls of Korean ...

    Stefano Porcelli, Soo-Jung Lee, Changsu Han… in Journal of Molecular Neuroscience (2018)

  3. No Access

    Article

    Genetic Variants Within Molecular Targets of Antipsychotic Treatment: Effects on Treatment Response, Schizophrenia Risk, and Psychopathological Features

    Schizophrenia (SCZ) is a common and severe mental disorder. Genetic factors likely play a role in its pathophysiology as well as in treatment response. In the present study, we investigated the effects of seve...

    Marco Calabrò, Stefano Porcelli, Concetta Crisafulli… in Journal of Molecular Neuroscience (2018)

  4. No Access

    Article

    Modulation of human longevity by SIRT3 single nucleotide polymorphisms in the prospective study “Treviso Longeva (TRELONG)”

    Human sirtuins are seven proteins with deacetylase activity that are emerging as key modulators of basic physiological functions. Some evidence links SIRT3 to longevity in mammals. This study aimed to investig...

    Diego Albani, Eleonora Ateri, Stefano Mazzuco, Alice Ghilardi, Serena Rodilossi… in AGE (2014)

  5. No Access

    Article

    Interleukin-1α, interleukin-1β and tumor necrosis factor-α genetic variants and risk of dementia in the very old: evidence from the “Monzino 80-plus” prospective study

    The association among single nucleotide polymorphisms in inflammatory genes as interleukin-1 alpha (IL-1α), interleukin-1 beta (IL-1β) or tumor necrosis factor alpha (TNF-α) and dementia has been explored mostly ...

    Diego Albani, Mauro Tettamanti, Sara Batelli, Letizia Polito, Sabrina Dusi… in AGE (2012)

  6. No Access

    Article

    Rosuvastatin and Thapsigargin Modulate γ-Secretase Gene Expression and APP Processing in a Human Neuroglioma Model

    Alzheimer's disease (AD) is a progressive neurodegenerative disorder leading to slow neuronal loss in several brain regions. It is characterised by the presence of cerebral senile plaques comprised of aggregat...

    Alessio Crestini, Paola Piscopo… in Journal of Molecular Neuroscience (2011)

  7. No Access

    Article

    Interleukin-6 plasma level increases with age in an Italian elderly population (“The Treviso Longeva”–Trelong–study) with a sex-specific contribution of rs1800795 polymorphism

    The transcription rate of interleukin-6 (IL-6) can be reduced by the C-allele of a polymorphism (rs1800795) located in the 5′-flanking region of the IL-6 gene (NM_000600), and IL-6 plasma levels increase with ...

    Diego Albani, Sara Batelli, Letizia Polito, Francesca Prato, Marzia Pesaresi… in AGE (2009)

  8. No Access

    Article

    Characterization of a gene highly expressed in the Brassica napus pistil that encodes a novel proline-rich protein

    Pis 30, a gene highly expressed in Brassica napus pistils and encoding a novel proline-rich protein was isolated and characterized. Sequences homologous to the Brassica Pis 30 gene were found only in Arabidopsis ...

    Elizabeth Foster, Madeleine Lévesque-Lemay… in Sexual Plant Reproduction (2005)

  9. No Access

    Article

    Characterization of genes expressed during the development ofBrassica napus pollen

    The study of the formation of pollen in plants has been the focus of extensive morphologic and cytologic observations. This complex developmental process requires the coordinated activity of both gametophytic ...

    Steven F. Fabijanski, Diego Albani, Laurian S. Robert, Paul G. Arnison in In Vitro – Plant (1992)