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A Systems Biology Approach for Identifying Hepatotoxicant Groups Based on Similarity in Mechanisms of Action and Chemical Structure

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  1. Article

    Open Access

    On the correlation between material-induced cell shape and phenotypical response of human mesenchymal stem cells

    Learning rules by which cell shape impacts cell function would enable control of cell physiology and fate in medical applications, particularly, on the interface of cells and material of the implants. We defin...

    Aliaksei S. Vasilevich, Steven Vermeulen, Marloes Kamphuis… in Scientific Reports (2020)

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  2. Article

    Open Access

    Dynamic adaptation of mesenchymal stem cell physiology upon exposure to surface micropatterns

    Human mesenchymal stem (hMSCs) are defined as multi-potent colony-forming cells expressing a specific subset of plasma membrane markers when grown on flat tissue culture polystyrene. However, as soon as hMSCs ...

    Nick R. M. Beijer, Zarina M. Nauryzgaliyeva, Estela M. Arteaga… in Scientific Reports (2019)

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  3. Article

    Open Access

    Identification of Sex-Specific Transcriptome Responses to Polychlorinated Biphenyls (PCBs)

    PCBs are classified as xenoestrogens and carcinogens and their health risks may be sex-specific. To identify potential sex-specific responses to PCB-exposure we established gene expression profiles in a popula...

    Almudena Espín-Pérez, Dennie G. A. J. Hebels, Hannu Kiviranta… in Scientific Reports (2019)

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