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Article
Open AccessOn the correlation between material-induced cell shape and phenotypical response of human mesenchymal stem cells
Learning rules by which cell shape impacts cell function would enable control of cell physiology and fate in medical applications, particularly, on the interface of cells and material of the implants. We defin...
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Article
Open AccessDynamic adaptation of mesenchymal stem cell physiology upon exposure to surface micropatterns
Human mesenchymal stem (hMSCs) are defined as multi-potent colony-forming cells expressing a specific subset of plasma membrane markers when grown on flat tissue culture polystyrene. However, as soon as hMSCs ...
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Article
Open AccessData-analysis strategies for image-based cell profiling
This Review covers the steps required to create high-quality image-based profiles from high-throughput microscopy images.