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Article
Open AccessFrequency and impact of medication reviews for people aged 65 years or above in UK primary care: an observational study using electronic health records
Medication reviews in primary care provide an opportunity to review and discuss the safety and appropriateness of a person’s medicines. However, there is limited evidence about access to and the impact of rout...
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Article
Open AccessA randomised controlled trial investigating the clinical and cost-effectiveness of Alpha-Stim AID cranial electrotherapy stimulation (CES) in patients seeking treatment for moderate severity depression in primary care (Alpha-Stim-D Trial)
Major depression is the second leading cause of years lost to disability worldwide and is a leading contributor to suicide. However, first-line antidepressants are only fully effective for 33%, and only 40% of...
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Article
Open AccessThe risk of all-cause and cause-specific mortality in people prescribed mirtazapine: an active comparator cohort study using electronic health records
Studies have reported an increased risk of mortality among people prescribed mirtazapine compared to other antidepressants. The study aimed to compare all-cause and cause-specific mortality between adults pres...
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Article
Open AccessSecondary care specialist visits made by children and young people prescribed antidepressants in primary care: a descriptive study using the QResearch database
Antidepressants may be used to manage a number of conditions in children and young people including depression, anxiety, and obsessive-compulsive disorder. UK guidelines for the treatment of depression in chil...