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  1. Article

    Open Access

    Role of p73 in Alzheimer disease: lack of association in mouse models or in human cohorts

    P73 belongs to the p53 family of cell survival regulators with the corresponding locus Trp73 producing the N-terminally distinct isoforms, TAp73 and DeltaNp73. Recently, two studies have implicated the murine Trp...

    Badri Vardarajan, David Vergote, Fadel Tissir, Mark Logue… in Molecular Neurodegeneration (2013)

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    Article

    Morphological and functional characterization of leech circulating blood cells: role in immunity and neural repair

    Unlike most invertebrates, annelids possess a closed vascular system distinct from the coelomic liquid. The morphology and the function of leech blood cells are reported here. We have demonstrated the presence...

    Céline Boidin-Wichlacz, David Vergote… in Cellular and Molecular Life Sciences (2012)

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    Chemokine Proteolytic Processing in HIV Infection: Neurotoxic and Neuroimmune Consequences

    Together with transcriptional and translational regulation, posttranslational modification is a pivotal mechanism regulating protein abundance and function. Proteolysis has been suggested to be the most import...

    David Vergote, Christopher M. Overall… in Chemokine Receptors and NeuroAIDS (2010)

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    Article

    (−)-Epigallocatechin (EGC) of Green Tea Induces Apoptosis of Human Breast Cancer Cells But Not of their Normal Counterparts

    (−)-Epigallocatechin (EGC), one of green tea polyphenols, has been shown to inhibit growth of cancer cells. However its mechanism of action is poorly known. We show here that EGC strongly inhibited the growth ...

    David Vergote, Cécile Cren-Olivé, Valérie Chopin… in Breast Cancer Research and Treatment (2002)