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  1. Article

    Open Access

    BRD4 promotes resection and homology-directed repair of DNA double-strand breaks

    Double-strand breaks (DSBs) are one of the most toxic forms of DNA damage and represent a major source of genomic instability. Members of the bromodomain and extra-terminal (BET) protein family are characteriz...

    John K. Barrows, Baicheng Lin, Colleen E. Quaas, George Fullbright… in Nature Communications (2022)

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  2. Article

    Open Access

    Uncoupling of p97 ATPase activity has a dominant negative effect on protein extraction

    p97 is a highly abundant, homohexameric AAA+ ATPase that performs a variety of essential cellular functions. Characterized as a ubiquitin-selective chaperone, p97 recognizes proteins conjugated to K48-linked p...

    Halley B. Rycenga, Kelly B. Wolfe, Elizabeth S. Yeh, David T. Long in Scientific Reports (2019)

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