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  1. No Access

    Article

    Marked neuropsychiatric involvement and dysmorphic features in nemaline myopathy

    Inherited nemaline myopathy is one of the most common congenital myopathies. This genetically heterogeneous disease is defined by the presence of nemaline bodies in muscle biopsy. The phenotypic spectrum is wi...

    Paulo Ribeiro Nóbrega, Jorge Luiz de Brito de Souza in Neurological Sciences (2024)

  2. No Access

    Article

    Role of biological effective dose for prediction of endocrine remission in acromegaly patients treated with stereotactic radiosurgery

    Stereotactic radiosurgery (SRS) can be used in acromegaly patients to achieve endocrine remission. In this study we evaluate the biological effective dose (BED) as a predictor of SRS outcomes for acromegaly.

    Chloe Dumot, David Schlesinger, Georgios Mantziaris, Sam Dayawansa, Zhiyuan Xu in Pituitary (2023)

  3. Article

    Open Access

    Chromosomal microarray analyses from 5778 patients with neurodevelopmental disorders and congenital anomalies in Brazil

    Chromosomal microarray analysis (CMA) has been recommended and practiced routinely since 2010 both in the USA and Europe as the first-tier cytogenetic test for patients with unexplained neurodevelopmental dela...

    Ana C. V. Krepischi, Darine Villela, Silvia Souza da Costa in Scientific Reports (2022)

  4. No Access

    Article

    Effect of distance from target on hypopituitarism after stereotactic radiosurgery for pituitary adenomas

    Delayed hypopituitarism is the most common complication after stereotactic radiosurgery (SRS) for pituitary adenomas. The aim of this study was to investigate the relationship between the distance from the hyp...

    Natasha Ironside, Harrison Snyder, Zhiyuan Xu in Journal of Neuro-Oncology (2022)

  5. Article

    Open Access

    Detection of germline variants in Brazilian breast cancer patients using multigene panel testing

    Genetic diversity of germline variants in breast cancer (BC) predisposition genes is unexplored in miscegenated populations, such those living in Latin America. We evaluated 1663 Brazilian BC patients, who und...

    Rodrigo Santa Cruz Guindalini, Danilo Vilela Viana in Scientific Reports (2022)

  6. Article

    Editorial: Radiosurgical induced malignancy associated with stereotactic radiosurgery

    Adomas Bunevicius, Styllianos Pikis, David Schlesinger in Acta Neurochirurgica (2021)

  7. No Access

    Article

    Leukoencephalopathy in long term brain metastases survivors treated with radiosurgery

    Brain metastases (BM) develop in 10–30 % of patients. Stereotactic radiosurgery (SRS) was shown to improve local control, and performance status, in certain cohorts of brain metastasis patients. The cumulative...

    Or Cohen-Inbar, Patrick Melmer, Cheng-chia Lee, Zhiyuan Xu in Journal of Neuro-Oncology (2016)

  8. No Access

    Article

    Gamma Knife radiosurgery for medically and surgically refractory prolactinomas: long-term results

    Prolactinomas are the most common functioning pituitary adenomas. Dopamine agonists (DA) are generally very effective in treating prolactinomas by inducing tumor volume regression and endocrine remission. A mi...

    Or Cohen-Inbar, Zhiyuan Xu, David Schlesinger, Mary Lee Vance in Pituitary (2015)

  9. Article

    Open Access

    Thermal dose and radiation dose comparison based on cell survival

    Meredith Lee, David Schlesinger, Gail ter Haar in Journal of Therapeutic Ultrasound (2015)

  10. Article

    Open Access

    In vivo low frequency MR-guided thalamotomy with focused ultrasound: thermal vsmechanical lesioning in pig brain

    Zhiyuan Xu, Carissa Carlson, John Snell, Matt Eames in Journal of Therapeutic Ultrasound (2015)

  11. No Access

    Article

    A microdeletion in Alzheimer’s disease disrupts NAMPT gene

    DARINE VILLELA, DAVID SCHLESINGER, CLAUDIA K. SUEMOTO in Journal of Genetics (2014)

  12. No Access

    Article

    Application of diffusion-weighted magnetic resonance imaging to predict the intracranial metastatic tumor response to gamma knife radiosurgery

    To evaluate the effect of stereotactic radiosurgery (SRS) on intracranial metastases with diffusion-weighted imaging/apparent diffusion coefficient maps. A total of 107 patients with 144 metastases larger than...

    Cheng-Chia Lee, Max Wintermark, Zhiyuan Xu, Chun-Po Yen in Journal of Neuro-Oncology (2014)

  13. No Access

    Chapter

    Elekta System

    Elekta AB has developed a wide range of products and accessories to enable highly accurate and precise delivery for stereotactic body radiation therapy (SBRT). In this chapter the specific systems designed and...

    Julian R. Perks, Megan E. Daly, David Schlesinger in Stereotactic Body Radiation Therapy (2012)

  14. No Access

    Article

    Outcomes of Gamma Knife surgery for craniopharyngiomas

    Gamma Knife surgery (GKS) has emerged as a valuable adjuvant treatment modality for recurrent or residual craniopharyngioma. However, prognostic factors pertaining to progression-free survival (PFS) remain poo...

    Zhiyuan Xu, Chun-Po Yen, David Schlesinger, Jason Sheehan in Journal of Neuro-Oncology (2011)

  15. No Access

    Article

    Recurrent astroblastoma treated with gamma knife radiosurgery

    Astroblastomas are exceedingly rare central nervous system tumors. Surgical resection is the standard initial treatment for astroblastomas. Still, some astroblastomas that have been completely resected recur. ...

    David Weintraub, Stephen J. Monteith, Chun Po Yen in Journal of Neuro-Oncology (2011)

  16. No Access

    Article

    The role of Gamma Knife surgery in the treatment of skull base chordomas

    Skull base chordomas are a rare neoplasm arising from the notochord. Although histologically benign, these tumors are locally aggressive and present significant management challenges. The current series descri...

    Kasandra Dassoulas, David Schlesinger, Chun Po Yen in Journal of Neuro-Oncology (2009)

  17. No Access

    Article

    TIM-4 is the ligand for TIM-1, and the TIM-1–TIM-4 interaction regulates T cell proliferation

    The newly identified TIM family of proteins is associated with regulation of T helper type 1 (TH1) and TH2 immune responses. TIM-1 is genetically linked to asthma and is a receptor for hepatitis A virus, but the ...

    Jennifer Hartt Meyers, Sumone Chakravarti, David Schlesinger in Nature Immunology (2005)