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    Living Reference Work Entry In depth

    Malignant Lesions of the Fallopian Tube

    It is now recognized that the fimbrial end of the fallopian tube is the source of many (and some believe all) “ovarian” pelvic high-grade serous carcinomas. The spectrum of serous tubal neoplasia includes p53 ...

    Brooke Liang, David L. Kolin, Brooke E. Howitt in Gynecologic and Obstetric Pathology

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    Living Reference Work Entry In depth

    Benign Lesions of the Fallopian Tube

    The fallopian tube is a tubular structure comprised of an outer muscularis layer and an inner mucosal plica epithelialized by ciliated columnar cells, secretory cells, and intercalated cells. Embryologically d...

    Brooke Liang, Christina Wei, David L. Kolin in Gynecologic and Obstetric Pathology

  3. Article

    Open Access

    A Replication stress biomarker is associated with response to gemcitabine versus combined gemcitabine and ATR inhibitor therapy in ovarian cancer

    In a trial of patients with high grade serous ovarian cancer (HGSOC), addition of the ATR inhibitor berzosertib to gemcitabine improved progression free survival (PFS) compared to gemcitabine alone but biomark...

    Panagiotis A. Konstantinopoulos, Alexandre André B. A. da Costa in Nature Communications (2021)

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    Chapter

    Fallopian Tube

    The fallopian tube contains a muscular wall and plicae lined by ciliated, tubal-type epithelium. While primary tumors of the fallopian tube are unusual, benign, borderline, and malignant tumors occur, many of ...

    David L. Kolin, Brooke E. Howitt in Gynecologic and Obstetric Pathology, Volume 2 (2019)

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    Article

    Expanding the Spectrum of Colonic Manifestations in Tuberous Sclerosis: L-Cell Neuroendocrine Tumor Arising in the Background of Rectal PEComa

    Tuberous sclerosis complex (TSC) is an autosomal dominant neurocutaneous condition that predisposes to numerous proliferative lesions, including perivascular epithelioid cell tumors (PEComas), such as lymphang...

    David L. Kolin, Kai Duan, Bo Ngan, J. Ted Gerstle in Endocrine Pathology (2018)

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    Article

    Prognostic significance of human tissue kallikrein-related peptidases 11 and 15 in gastric cancer

    Human tissue kallikrein-related peptidases (KLK) are a group of 15 serine proteases which have been investigated as potential cancer biomarkers. This study determined the prognostic significance of KLK 11 and ...

    David L. Kolin, Keiyan Sy, Fabio Rotondo, Mena N. Bassily, Kalman Kovacs in Tumor Biology (2016)

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    Article

    Advances in Image Correlation Spectroscopy: Measuring Number Densities, Aggregation States, and Dynamics of Fluorescently labeled Macromolecules in Cells

    A brief historical outline of fluorescence fluctuation correlation techniques is presented, followed by an in-depth review of the theory and development of image correlation techniques, including: image correl...

    David L. Kolin, Paul W. Wiseman in Cell Biochemistry and Biophysics (2007)