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    Article

    The Effects of N(4-Methylphenyl)diphenimide on Lipid Metabolism of Sprague Dawley Rats

    N(4-Methylphenyl)diphenimide proved to be an effective hypolipidemic agent in rats at 10 and 20 mg/kg/day. Both serum cholesterol and triglyceride levels were reduced significantly. Decreases in tissue lipids a....

    Iris H. Hall, O. T. Wong, Rupendra Simlot, David J. Reynolds in Pharmaceutical Research (1992)

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    Hypolipidemic Activity of o-(N-Phthalimido)acetophenone in Sprague Dawley Rats

    o-(N-Phthalimido)acetophenone has proven to be an effective hypolipidemic agent in rats at 20 mg/kg/ day orally. The agent suppressed the activity of the rate-limiting enzyme of the liver involved in de novo syn...

    Iris H. Hall, David J. Reynolds, Oi T. Wong, C. Brent Oswald in Pharmaceutical Research (1987)

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    Article

    Synthesis and Hypolipidemic Activity of 3-Imino-l-oxoisoindolines in Rodents

    A series of substituted 3-imino-l-oxoisoindolines derivatives demonstrated significant hypolipidemic activity, lowering both serum cholesterol and triglycerides levels after 16 days of dosing at 20 mg/kg/ day ...

    Akula R. K. Murthy, Oi T. Wong, David J. Reynolds, Iris H. Hall in Pharmaceutical Research (1987)