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Article
Open AccessCoordinated wound responses in a regenerative animal-algal holobiont
Animal regeneration involves coordinated responses across cell types throughout the animal body. In endosymbiotic animals, whether and how symbionts react to host injury and how cellular responses are integrat...
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Article
Open Accessi-shaped antibody engineering enables conformational tuning of biotherapeutic receptor agonists
The ability to leverage antibodies to agonize disease relevant biological pathways has tremendous potential for clinical investigation. Yet while antibodies have been successful as antagonists, immune mediator...
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Article
Local models for Galois deformation rings and applications
We construct projective varieties in mixed characteristic whose singularities model, in generic cases, those of tamely potentially crystalline Galois deformation rings for unramified extensions of ...
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Article
Human melanocyte development and melanoma dedifferentiation at single-cell resolution
In humans, epidermal melanocytes are responsible for skin pigmentation, defence against ultraviolet radiation and the deadliest common skin cancer, melanoma. Although there is substantial overlap in melanocyte...
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Article
Open AccessDelineating patterns of sexualized substance use and its association with sexual and mental health outcomes among young gay, bisexual and other men who have sex with men in Singapore: a latent class analysis
Young gay, bisexual, and other men who have sex with men (YMSM) are vulnerable to the risks associated with sexualized substance use. This is a novel study in Singapore that aims to classify patterns of sexual...
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Article
Open AccessTwo year follow up of supercapsular percutaneously assisted total hip arthroplasty
Dislocation after primary total hip arthroplasty (THA) has an incidence of 2–3%. Approximately 77% of dislocations occur within the first year after surgery. The SuperPATH technique is a minimally invasive app...
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Article
Open AccessAssociation between sexual orientation acceptance and suicidal ideation, substance use, and internalised homophobia amongst the pink carpet Y cohort study of young gay, bisexual, and queer men in Singapore
Gay, bisexual and queer (GBQ) men are frequently subjected to minority stressors that have negative impacts on their health. Milestones that include the acceptance and disclosure of sexual identity amongst GBQ...
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Article
Open AccessSocial capital and chemsex initiation in young gay, bisexual, and other men who have sex with men: the pink carpet Y cohort study
Young gay, bisexual, and other men who have sex with men (YMSM) are especially vulnerable to the risks associated with sexualized substance use, or ‘chemsex’. Engaging in chemsex established as a major risk fa...
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Article
Lattices in the cohomology of U(3) arithmetic manifolds
Under hypotheses required for the Taylor–Wiles method, we prove for forms of U(3) which are compact at infinity that the lattice structure on upper alcove algebraic vectors or on principal series types given by t...
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Article
Potentially crystalline deformation rings and Serre weight conjectures: shapes and shadows
We prove the weight part of Serre’s conjecture in generic situations for forms of U(3) which are compact at infinity and split at places dividing p as conjectured by Herzig (Duke Math J 149(1):37–116, 2009). We a...
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Article
Locating and parsing bibliographic references in HTML medical articles
The set of references that typically appear toward the end of journal articles is sometimes, though not always, a field in bibliographic (citation) databases. But even if references do not constitute such a fi...
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Article
Open AccessGlucose Toxicity: a case report
Toxicity to glucose is not a normal state, however, it has been reported that after certain individuals ingest sugar, they produce excess tumor necrosis factor.
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Chapter and Conference Paper
Text Verification in an Automated System for the Extraction of Bibliographic Data
An essential stage in any text extraction system is the manual verification of the printed material converted by OCR. This proves to be the most labor-intensive step in the process. In a system built and deplo...