4 Result(s)
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Article
Open AccessGenome edited sheep and cattle
Genome editing tools enable efficient and accurate genome manipulation. An enhanced ability to modify the genomes of livestock species could be utilized to improve disease resistance, productivity or breeding ...
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Article
Strategies for selection marker-free swine transgenesis using the Slee** Beauty transposon system
Swine transgenesis by pronuclear injection or cloning has traditionally relied on illegitimate recombination of DNA into the pig genome. This often results in animals containing concatemeric arrays of transgen...
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Efficient mammalian germline transgenesis by cis-enhanced Slee** Beauty transposition
Heightened interest in relevant models for human disease increases the need for improved methods for germline transgenesis. We describe a significant improvement in the creation of transgenic laboratory mice a...
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Article
Open AccessEnzymatic engineering of the porcine genome with transposons and recombinases
Swine is an important agricultural commodity and biomedical model. Manipulation of the pig genome provides opportunity to improve production efficiency, enhance disease resistance, and add value to swine produ...
