28 Result(s)
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Article
Open AccessMetabolomics reveals that Curcuma longa and demethoxycurcumin inhibit HCT116 human colon cancer cell growth
Studies on the use of natural products to treat cancer are ongoing, and turmeric (Curcuma longa L.), a medicinal crop, is known for various effects including anticancer activity. In this study, the inhibitory eff...
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Open AccessEvaluation of obesity prevention effect of black ginseng on serum, liver, and hypothalamus of mice on a high-fat diet using a metabolomics approach
Black ginseng is being studied to prevent obesity caused by a high-fat diet (HFD). The aim of this study was to evaluate the obesity-preventing effect of black ginseng extract (BGE) in the serum, liver, and hy...
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Open AccessAnti-inflammatory components isolated from Atractylodes macrocephala in LPS-induced RAW264.7 macrophages and BV2 microglial cells
The phytochemical investigation on the methanol extract of the rhizomes of Atractylodes macrocephala resulted in the discovery of one new compound 9α-hydroxyatractylenolide (1) and 21 known compounds including at...
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Open AccessCorrection to: New phenylalkanoids from the rhizome of Cnidium officinalis Makino
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Open AccessNew phenylalkanoids from the rhizome of Cnidium officinalis Makino
Cnidium officinalis rhizomes were immersed in 80% MeOH. The extract was fractionated to water, n-butanol, and ethyl acetate fractions (Fr). Open column chromatography was repeatedly carried out on n-butanol and e...
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Open AccessNew dibenzocyclooctadiene lignan from Schisandra chinensis (Turcz.) Baill. fruits
Repeated column chromatography using Sephadex LH-20, silica gel (SiO2), and octadecyl SiO2 (ODS) as well as preparative HPLC column chromatography led to isolation of a new dibenzocyclooctadiene lignan along with...
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Open AccessCorrection to: Dibenzocyclooctadiene lignans from the fruits of Schisandra chinensis and their cytotoxicity on human cancer cell lines
An amendment to this paper has been published and can be accessed via the original article.
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Article
Open AccessMachine learning for a rapid discrimination of ginseng cultivation age using 1H-NMR spectra
The scientific and systematic classification of cultivation age is important for preventing age falsification and ensuring the quality of ginseng. Therefore, we applied deep learning to classify the cultivatio...
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Open AccessDibenzocyclooctadiene lignans from the fruits of Schisandra chinensis and their cytotoxicity on human cancer cell lines
Repeated chromatographic separations of the EtOAc fraction of Schisandra chinensis fruits on silica gel, octadecyl silica gel, and Sephadex LH-20 led to the isolation and identification of seven dibenzocyclooctad...
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Article
Open AccessSimultaneous determination of various platycosides in Four Platycodon grandiflorum cultivars by UPLC-QTOF/MS
In Platycodi Radix (root of Platycodon grandiflorum), there are a number of platycosides that consist of a pentacyclic triterpenoid aglycone and two sugar moieties. Due to the pharmacological activities of platyc...
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Open AccessPharmacological activity and quantitative analysis of flavonoids isolated from the flowers of Begonia semperflorens Link et Otto
Begonia semperflorens Link et Otto has been broadly raised up for ornamental purpose as well comestible blossom. As the reproductive structures of phanerogams, flowers contain various secondary metabolites and ha...
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Article
Phenylpropanoids from Lilium Asiatic hybrid flowers and their anti-inflammatory activities
Three phenylpropanoids were isolated from the flowers of Lilium Asiatic hybrids through repeated silica gel or octadecyl silica gel column chromatographies. The chemical structures were determined to be 1-O-trans
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Article
New hydroxy fatty acid from the root bark of Morus alba L.
A new hydroxyl fatty acid, named sangbaimoric acid (1), was isolated from the root bark of Morus alba L. The chemical structure of compound 1 was established as 2-methoxyoctadeca-3Z,5Z-dienoic acid on the basis o...
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New tocopherol analogue with radical-scavenging activity from the peels of Citrus unshiu Marcovich
One new tocopherol analogue, methoxytocopherol (1), and two known analogues, α-tocopherol (2) and γ-tocopherol (3), were isolated from the peels of Citrus unshiu Marcovich. The chemical structures of compounds 1–...
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Article
Insecticidal alkaloids from the seeds of Macleaya cordata on cotton aphid (Aphis gossypii)
Alcohol extracts from the seeds of Macleaya cordata have shown a significant insecticidal effect against the growth of the cotton aphid, Aphis gossypii Glover. In this study, we aimed to isolate the principal com...
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Flavonoid glycosides from the fruit of Rhus parviflora and inhibition of cyclin dependent kinases by hyperin
Chrysoeriol-7-O-β-d-glucopyranoside (1), luteolin-7-O-β-d-glucopyranoside (2), quercetin-3-O-β-d-glucopyranoside (3), quercetin-3-O-β-d-galactopyranoside (4), and quercetin-3-O-α-l-rhamnopyranoside (5) were isola...
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Article
Fucosterols from Hizikia fusiformis and their proliferation activities on osteosarcoma-derived cell MG63
Four fucosterol derivatives were isolated from the ethyl acetate fraction of Hizikia fusiformis. The chemical structures of the sterols were elucidated as fucosterol (1), a mixture of 24R,28R- and 24S,28R-epoxy-2...
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Article
Cytotoxic and neuroprotective biflavonoids from the fruit of Rhus parviflora
Six biflavonoids, succedaneaflavanone (1), mesuaferrone B (2), rhusflavanone (3), rhusflavone (4), agathisflavone (5), and cupressuflavone (6), were isolated from the fruits of Rhus parviflora. The chemical struc...
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Constituents of Machilus thunbergii bark and inhibition of cyclin-dependent kinases (CDKs) by procyanidin B2
Stigmast-5-en-3β,7β-diol (1), stigmast-5-en-3β,7α-diol (2), (+)-isolariciresinol-9-O-β-d-xylopyranoside (3), procyanidin B2 (4), and epicatechin-(4β→8)-epicatechin-(4β→6)-epicatechin (5) were isolated for the fir...
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Article
A New flavonolignan from the aerial Parts of Oryza sativa L. inhibits nitric oxide production in RAW 264.7 macrophage cells
Fresh and chopped aerial parts of Oryza sativa were extracted in 80% aqueous mehthanol, and the concentrated extract was successively partitioned using n-hexane, ethyl acetate (EtOAc), nbutanol, and H2O. From the...
