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Open AccessCorrection to: New phenylalkanoids from the rhizome of Cnidium officinalis Makino
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Open AccessNew phenylalkanoids from the rhizome of Cnidium officinalis Makino
Cnidium officinalis rhizomes were immersed in 80% MeOH. The extract was fractionated to water, n-butanol, and ethyl acetate fractions (Fr). Open column chromatography was repeatedly carried out on n-butanol and e...
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Open AccessSafety, tolerability of ES16001, a novel varicella zoster virus reactivation inhibitor, in healthy adults
Herpes zoster (HZ), or shingles, is a clinical syndrome resulting from the reactivation of latent varicella zoster virus (VZV) within the sensory ganglia. We evaluated the safety and tolerability of ES16001 (e...
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Open AccessNew dibenzocyclooctadiene lignan from Schisandra chinensis (Turcz.) Baill. fruits
Repeated column chromatography using Sephadex LH-20, silica gel (SiO2), and octadecyl SiO2 (ODS) as well as preparative HPLC column chromatography led to isolation of a new dibenzocyclooctadiene lignan along with...
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Open AccessSpermidine-induced recovery of human dermal structure and barrier function by skin microbiome
An unbalanced microbial ecosystem on the human skin is closely related to skin diseases and has been associated with inflammation and immune responses. However, little is known about the role of the skin micro...
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Open AccessCorrection to: Dibenzocyclooctadiene lignans from the fruits of Schisandra chinensis and their cytotoxicity on human cancer cell lines
An amendment to this paper has been published and can be accessed via the original article.
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Open Accessβ-Glucogallin isolated from Fusidium coccineum and its enhancement of skin barrier effects
Soil has been used for treatment of wound and skin diseases and for cosmetic purposes. Fusidium coccineum (FC) SA-1FC (Ascomycota) is a fungus found in nature, and its by-products are present in humid soils with ...
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Open AccessCritical enzymes for biosynthesis of cucurbitacin derivatives in watermelon and their biological significance
Various cucurbitacins have been isolated, and their structures have been elucidated. Owing to their economic potential and importance as active pharmacological compounds, their cytotoxicity in various cancer c...
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Open AccessDibenzocyclooctadiene lignans from the fruits of Schisandra chinensis and their cytotoxicity on human cancer cell lines
Repeated chromatographic separations of the EtOAc fraction of Schisandra chinensis fruits on silica gel, octadecyl silica gel, and Sephadex LH-20 led to the isolation and identification of seven dibenzocyclooctad...
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A New Neolignan Glucoside from the Stems of “Baekma” Cultivar, Chrysanthemum morifolium
A new neolignan glucoside has been isolated from Chrysanthemum morifolium ‘Baekma’ cultivar through repeated silica gel and octadecyl silica gel (ODS) column chromatographies. On the basis of spectroscopic dat...
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Enzymatic synthesis of β-galactosyl fucose using recombinant bifidobacterial β-galactosidase and its prebiotic effect
Breast-fed infants have Bifidobacterium-rich gut microbiota compared to infants fed formula. Fucosylated oligosaccharides are the major components of human milk oligosaccharide (HMO) which confer various benefici...
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New Lignan from the Flowers of Forsythia koreana
A new lignan (1) was isolated from the flowers of Forsythia koreana along with one known lignan, 4,4′-di-O-β-D-glucosylpinoresinol (2). The molecular structures were determined using spectral methods. These compo...
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Open AccessA 1,1′-biuracil from Epidermidibacterium keratini EPI-7 shows anti-aging effects on human dermal fibroblasts
Our previous study we isolated novel bacterial stain, Epidermidibacterium keratini, called EPI-7T from skin samples. Repeated column separation yielded one new pyrimidine compound, 1,1′-biuracil, from EPI-7T cult...
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Open AccessRecovery effect of lignans and fermented extracts from Forsythia koreana flowers on pancreatic islets damaged by alloxan in zebrafish (Danio rerio)
Repeated column separation yielded four enterolactone type lignans from Forsythia koreana flowers (FKF), whose chemical structures were identified using several spectral technics. FKF MeOH extract (FKFM) and four...
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Phenylethanoid glycoside from Forsythia koreana (Oleaceae) flowers shows a neuroprotective effect
A repeated column chromatography for Forsythia koreana Nakai. flowers afforded a phenylethane glycoside, which was identified as 8′-(3,4-dihydroxyphenyl)ethyl-O-α-l-rhamnopyranosyl-(1 → 4)-2-O-(E)-caffeoyl-α-l-ar...
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Glycerides isolated from the aerial parts of Malva verticillata cause immunomodulation effects via splenocyte function and NK anti-tumor activity
A preliminary study revealed that a 10 µg/mL n-BuOH fraction of Malva verticillata aerial parts significantly enhanced splenocyte proliferation and induced significant enhancement of natural-killer (NK) cell acti...
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Skin depigmenting action of silkworm (Bombyx mori L.) drop**s in zebrafish
The excrement of silkworms (Bombyx mori L.), referred to here as silkworm drop**s (SDs), is used as a traditional drug in eastern medicine to treat skin diseases such as urticaria and atopy. However, the depigm...
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Phenylpropanoids from Lilium Asiatic hybrid flowers and their anti-inflammatory activities
Three phenylpropanoids were isolated from the flowers of Lilium Asiatic hybrids through repeated silica gel or octadecyl silica gel column chromatographies. The chemical structures were determined to be 1-O-trans
