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  1. No Access

    Chapter and Conference Paper

    Impact of the IDO2 blocker D-1-methyltryptophan on the IDO activity of human tumors and dendritic cells

    Clinical phase-I-trials with cancer patients have been started with the aim of inducing tumor immunity by blocking the immunosuppressive action of indoleamine-2,3-dioxygenase (IDO) with the IDO2-inhibitor dextro-...

    Dr. med. S. Löb, P. Terness, D. Zieker… in Chirurgisches Forum und DGAV Forum 2009 (2009)

  2. No Access

    Chapter and Conference Paper

    Laktat moduliert die Genexpression mesenchymaler Stammzellen (MSC)

    Introduction: Surgical wounds are characterized by elevated tissue lactate concentrations. This accumulated lactate is capable of stimulating collagen synthesis and new vessel growth as well. Rec...

    D. Zieker, R. Schäfer, S. Coerper, A. Königsrainer, H. Northoff… in Chirurgisches Forum 2008 (2008)