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Article
Lebermetastasen neuroendokriner Tumoren
Neuroendokrine Lebermetastasen (NELM) sind in Bezug auf die klinische Präsentation und die Prognose sehr heterogen. Die Behandlung von NELM erfordert einen multidisziplinären Ansatz und Patienten mit NELM soll...
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Article
Open AccessTechnology development of hyperthermic pressurized intraperitoneal aerosol chemotherapy (hPIPAC)
Optimized drug delivery systems are needed for intraperitoneal chemotherapy. The aim of this study was to develop a technology for applying pressurized intraperitoneal aerosol chemotherapy (PIPAC) under hypert...
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Article
Hernia repair and simultaneous continuous ambulatory peritoneal dialysis (CAPD) catheter implantation: feasibility and outcome
Occurrence of abdominal wall hernias during and before peritoneal dialysis constitutes a pivotal role in treatment discontinuation, failure, and exclusion from this dialysis method. We herein present a single-...
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Article
Correction to: Acute and Elective Laparoscopic Resection for Complicated Sigmoid Diverticulitis: Clinical and Histological Outcome
Dorina Windecker is added as an author to this paper.
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Article
Rolle des Radiologen in der Chirurgie kolorektaler Lebermetastasen
Die radikale chirurgische Behandlung kolorektaler Lebermetastasen ist die einzige kurative Therapieoption für betroffene Patienten.
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Article
Therapie der nichtvarikösen oberen gastrointestinalen Blutung: endoluminal – endovaskulär – chirurgisch
Die nichtvariköse obere gastrointestinale Blutung (OGIB) hat eine hohe Letalität. Hämatemesis ggf. mit Meläna sind die Leitsymptome. Peptische Ulzerationen sind neben (erosiven) Entzündungen häufig, seltener s...
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Article
Intrathorakale Anastomoseninsuffizienz nach Ösophagus- und Kardiaresektion
Die Anastomoseninsuffizienz ist nach wie vor die Hauptursache für Mortalität nach Ösophagus- und Kardiaresektion. Da sich in Deutschland die Endoskopie als erste diagnostische Maßnahme beim Verdacht auf eine I...
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Article
Oligometastasierung beim Magen- und Ösophaguskarzinom
Die Rolle der Chirurgie gewinnt auch in metastasierten Tumorstadien zunehmend an Bedeutung. Bei kolorektalen Karzinomen mit einer limitierten Metastasierung kann sowohl in der synchronen als auch metachronen S...
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Article
Open AccessImpact of surgical resection extension on outcome for primary well-differentiated thyroid cancer—a retrospective analysis
The surgical resection extension in well-differentiated thyroid cancer is controversially discussed with the possibility of an overtreatment on the one hand against the risk of local disease recurrence. The ai...
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Article
Open AccessThe protective effect of human renal sinus fat on glomerular cells is reversed by the hepatokine fetuin-A
Renal sinus fat (RSF) is a perivascular fat compartment located around renal arteries. In this in vitro and in vivo study we hypothesized that the hepatokine fetuin-A may impair renal function in non alcoholic fa...
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Article
Comparison of clinical outcome of laparoscopic versus open appendectomy for complicated appendicitis
Laparoscopic appendectomy is now the treatment of choice in uncomplicated appendicitis. To date its importance in the treatment of complicated appendicitis is not clearly defined.
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Article
Pancreas-preserving surgical management of grade-C pancreatic fistulas after pancreatic head resection by external wirsungostomy
Completion pancreatectomy for grade-C pancreatic fistula is associated with unacceptably high mortality and therefore this strategy should be reassessed. This study presents an update of our experience with a ...
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Article
Selective, efficient modulation of activated CD4+ αβT cells by the novel humanized antibody GZ-αβTCR targeting human αβTCR
Allograft rejection and immunosuppression are two major issues in transplantation medicine. The specific targeting of alloreactive T cells, the initiators and promoters of allograft rejection, would be a promi...
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Article
Full Thickness Resection Device
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Article
A non-comparative phase II study of dose intensive chemotherapy with doxorubicin and ifosfamide followed by high dose ICE consolidation with PBSCT in non-resectable, high grade, adult type soft tissue sarcomas
The objective was to determine the role of dose intensive induction chemotherapy in patients with soft tissue sarcomas (STS) that were considered unresectable. Treatment consisted of 2–3 cycles of doxorubicin ...
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Article
Successful ganciclovir treatment of primary cytomegalovirus infection containing the UL97 mutation N510S in an intestinal graft recipient
In solid organ transplantation, human cytomegalovirus (HCMV) is considered to be the most important viral pathogen. We report a case of a CMV R−/D+ small intestine transplant recipient with a primary CMV infec...
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Article
Open AccessAltered expression of gustatory-signaling elements in gastric tissue of morbidly obese patients
Sensing of nutrients in the stomach is of crucial importance for the regulation of ingestive behavior especially in the context of metabolic dysfunctions such as obesity. Cells in the gastric mucosa with taste...
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Article
Gene expression analysis in chronic postradiation proctopathy
Radiotherapy is one of the important treatment modalities for tumors of pelvic organs. The fixed location of the rectum and its anatomic relationship with other pelvic organs makes it prone to radiation injury...
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Article
Visceral obesity modulates the impact of apolipoprotein C3 gene variants on liver fat content
It has not been solved whether subjects carrying the minor alleles of the −455T>C or −482C>T single nucleotide polymorphisms (SNPs) in the apolipoprotein-C3-gene (APOC3) have an increased risk for develo** fatt...
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Article
The secretion pattern of perivascular fat cells is different from that of subcutaneous and visceral fat cells
We have previously found that the mass of perivascular adipose tissue (PVAT) correlates negatively with insulin sensitivity and post-ischaemic increase in blood flow. To understand how PVAT communicates with v...
