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Article
Open AccessTumour cell contamination of autologous stem cells grafts in high-risk neuroblastoma: the good news?
We analysed the effect of graft-contaminating tumour cells on the long-term survival of 24 patients with high-risk neuroblastoma and found that patients whose grafts contained detectable neuroblastoma cells ha...
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Article
Multiple gene expression analysis reveals distinct differences between G2 and G3 stage breast cancers, and correlations of PKC η with MDR1, MRP and LRP gene expression
A possible link between protein kinase C (PKC) and P-glycoprotein (P-gp)-mediated-multidrug resistance (MDR) was assumed from studies on MDR cell lines selected in vitro. The functional relevance of PKC for th...
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Article
Mdr1/P-glycoprotein, topoisomerase, and glutathione-S-transferase π gene expression in primary and relapsed state adult and childhood leukaemias
In a variety of adult and childhood leukaemia cell samples collected at different states of the disease, we analysed in a series of sequentially performed slot-blot or Northern-blot hybridisation experiments t...