Skip to main content

11 Result(s)

within D. B. Davies Remove this filter Life Sciences Remove this filter

and

  1. No Access

    Article

    General analysis of competitive binding in drug–interceptor–DNA systems

    A general model of competitive binding in drug–interceptor–DNA systems has been developed in order to quantify both the interceptor and protector mechanisms. The model involves full parameterization of the bas...

    A. S. Buchelnikov, A. A. Hernandez Santiago… in European Biophysics Journal (2012)

  2. No Access

    Article

    Quantification of the interceptor action of caffeine on the in vitro biological effect of the anti-tumour agent topotecan

    Using published in vitro data on the dependence of the percentage of apoptosis induced by the anti-cancer drug topotecan in a leukaemia cell line on the concentration of added caffeine, and a general model of ...

    M. P. Evstigneev, A. A. Mosunov, V. P. Evstigneev… in European Biophysics Journal (2011)

  3. No Access

    Article

    Complexation of anthracycline drugs with DNA in the presence of caffeine

    The competitive binding of anthracycline antitumour drugs, [daunomycin (DAU), doxorubicin (DOX) or nogalamycin (NOG)], with caffeine (CAF) to a model DNA oligomer has been investigated by 500 MHz 1H NMR spectrosc...

    M. P. Evstigneev, V. V. Khomich, D. B. Davies in European Biophysics Journal (2006)

  4. No Access

    Article

    Complexation of the quinolone antibiotic norfloxacin with DNA

    1H-NMR spectroscopy (500 MHz) was used to study the complexation of the antibacterial agent norfloxacin (NOR) with DNA tetramers 5′-d(TpGpCpA) and 5′-d(CpGpCpG) in aqueous solution. For t...

    M. P. Evstigneev, S. F. Baranovsky, K. A. Rybakova, D. B. Davies in Molecular Biology (2006)

  5. No Access

    Article

    A Structural and Thermodynamic Analysis of Novatrone and Flavin Mononucleotide Heteroassociation in Aqueous Solution by 1H NMR Spectroscopy

    A heteroassociation of the antitumor antibiotic novatrone (NOV) and flavin mononucleotide (FMN) in aqueous solution was studied by one- and two-dimentional 1H NMR spectroscopy (500 MHz) to elucidate the molecular...

    A. N. Veselkov, M. P. Evstigneev… in Russian Journal of Bioorganic Chemistry (2005)

  6. No Access

    Article

    Structural analysis of the complex of phenoxazone antibiotic actinocyl-bis(2-dimethylaminoethyl)amide with deoxytetranucleotide 5′-d(TpGpCpA) by two-dimensional 1H-NMR spectroscopy and molecular mechanics

    The spatial structure of an intercalated complex of the synthetic phenoxazone antibiotic actinocyl-bis-(2-dimethylaminoethyl)amide (ActII) and the self-complementary deoxytetranucleotide 5′-d(TpGpCpA) was stud...

    A. N. Veselkov, L. N. Djimant, K. A. Veselkov, D. B. Davies in Molecular Biology (2005)

  7. No Access

    Article

    Heteroassociation of Caffeine with the Antibiotic Actinocyl- bis(3-dimethylaminopropylamine) in Aqueous Solution: 1H NMR Analysis

    The heteroassociation of caffeine (CAF) and the synthetic antibiotic actinocyl-bis(3-dimethylaminopropylamine) (ACT) was studied in aqueous solution by one- and two-dimensional 1H NMR spectroscopy at 500 MHz. The...

    A. N. Veselkov, A. O. Lantushenko… in Russian Journal of Bioorganic Chemistry (2002)

  8. No Access

    Article

    NMR Study of Complexation of Aromatic Ligands with Heptadeoxynucleotide 5"-d(GCGAAGC) Forming Stable Hairpin Structure in Aqueous Solution

    Complex formation of hairpin-producing heptadeoxynucleotide 5"-d(GCGAAGC) with aromatic molecules: acridine dye proflavine and anthracycline antibiotic daunomycin was studied by one-dimensional 1H NMR and two-dim...

    A. N. Veselkov, R. J. Eaton, A. V. Semanin, V. I. Pakhomov… in Molecular Biology (2002)

  9. No Access

    Article

    The Self-Association of Antibiotic Actinocyl-bis(3-dimethylaminopropylamine) in Aqueous Solution: A 1H NMR Analysis

    The self-association of the synthetic antibiotic actinocyl-bis(3-dimethylaminopropylamine) was studied in aqueous solution by one- and two-dimensional 1H NMR spectroscopy at 500 MHz. The two-dimensional homonucle...

    D. A. Veselkov, A. O. Lantushenko, D. B. Davies… in Russian Journal of Bioorganic Chemistry (2002)

  10. No Access

    Article

    NMR Study of Daunomycin Complexation with Hexadeoxynucleotide 5"-d(TpApCpGpTpA) in Aqueous Solution

    Self-association of hexadeoxynucleotide 5"-d(TpApCpGpTpA) and its complexation with antitumor antibiotic daunomycin were studied by one- and two-dimensional homonuclear 1H NMR spectroscopy and heteronuclear 1H–31

    A. N. Veselkov, R. J. Eaton, V. I. Pakhomov, A. V. Semanin… in Molecular Biology (2001)

  11. No Access

    Article

    The value of nitrogen applied to wheat during early development

    Forty eight field trials were conducted at sites representing the major arable areas of the UK to test the effectiveness of nitrogen applied during early growth. A family of linear + exponential curves of cons...

    R. Sylvester-Bradley, D. B. Davies, C. Dyer, C. Rahn… in Nutrient Cycling in Agroecosystems (1996)