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  1. No Access

    Article

    XRCC4 in G1 suppresses homologous recombination in S/G2, in G1 checkpoint-defective cells

    Non-homologous end joining (NHEJ) and homologous recombination (HR) are two pathways that can compete or cooperate for DNA double-strand break (DSB) repair. NHEJ was previously shown to act throughout the cell...

    Y Saintigny, F Delacôte, D Boucher, D Averbeck, B S Lopez in Oncogene (2007)

  2. No Access

    Article

    Recent reports on the effect of low doses of ionizing radiation and its dose–effect relationship

    Recently, the risk associated with low doses of ionizing radiation has gained new interest. Here, we analyze and discuss the major differences between two reports recently published on this issue; the report o...

    M. Tubiana, A. Aurengo, D. Averbeck, R. Masse in Radiation and Environmental Biophysics (2006)

  3. No Access

    Article

    The pso4-1 mutation reduces spontaneous mitotic gene conversion and reciprocal recombination in Saccharomyces cerevisiae

    Spontaneous mitotic recombination was examined in the haploid pso4-1 mutant of Saccharomyces cerevisiae and in the corresponding wild-type strain. Using a genetic system involving a duplication of the his4 gene i...

    L. B. Meira, M. B. Fonseca, D. Averbeck… in Molecular and General Genetics MGG (1992)

  4. No Access

    Article

    Repair of 8-methoxypsoralen photoinduced cross-links in yeast

    The repair of interstrand cross-links induced by 8-methoxypsoralen plus UVA (365 nm) radiation DNA was analyzed in diploid strains of the yeast Saccharomyces cerevisiae. The strains employed were the wild-type D7

    E. Cundari, M. Dardalhon, S. Rousset, D. Averbeck in Molecular and General Genetics MGG (1991)

  5. No Access

    Chapter

    Mutagenic Effects of Psoralen-Induced Photoadducts and their Repair in Eukaryotic Cells

    Work on the mutagenesis of psoralens (furocoumarins) on eukaryotic cells can be taken as an example for the intimate connection between fundamental and applied aspects in psoralen research. In fact, due to the...

    D. Averbeck, M. Dardalhon, N. Magaña-Schwencke in Photobiology (1991)

  6. No Access

    Chapter

    Processing of Photoinduced Cross-Links and Monoadducts in Human Cell DNA: Genetic and Molecular Features

    The interest in cellular processing of DNA interstrand cross-links and monoadducts steins from a number of observations including their induction by a variety of agents present in the human environment. Indeed...

    E. Moustacchi, D. Papadopoulo, D. Averbeck… in DNA Repair Mechanisms and Their Biological… (1989)

  7. No Access

    Chapter

    Phenotypic and Genetic Heterogeneity in Fanconi Anemia, Fate of Cross-Links, and Correction of the Defect by DNA Transfection

    The isolation and characterization of mutants unusually susceptible to DNA- damaging agents in prokaryotes and in lower eukaryotes helped considerably in the unraveling of the mystery of the genetic control me...

    E. Moustacchi, D. Averbeck, C. Diatloff-Zito, D. Papadopoulo in Fanconi Anemia (1989)

  8. No Access

    Chapter and Conference Paper

    Mutagenesis by Psoralens on Eukaryotic Cells

    Psoralens (furocoumarins) of natural or synthetic origin show photosensitizing activity on biological systems in the presence of long-wave ultraviolet radiation (320–400 nm) (UVA) (Musajo and Rodighiero 1972, ...

    D. Averbeck in Photosensitisation (1988)

  9. No Access

    Chapter and Conference Paper

    Photomutagenicity Induced by Psoralens: Modulation of the Photomutagenic Response in Eukaryotes

    Photoreactive furocoumarins (psoralens), such as 8-methoxypsoralen (8-MOP) and 5-methoxypsoralen (5-MOP), present in many plant extracts (Scott et al. 1976), are used in the photochemotherapeutic treatment (PU...

    D. Averbeck in The Target Organ and the Toxic Process (1988)

  10. No Access

    Chapter

    Photobiology of Furocoumarins

    The photobiology of fucoroumarins has been covered by a number of reviews (1–4). In recent years we observed a rapid evolution in the knowledge on naturally occurring or synthetic furocoumarins which in the pr...

    D. Averbeck in Trends in Photobiology (1982)

  11. No Access

    Article

    Studies on possible genetic effects of microwaves in procaryotic and eucaryotic cells

    The biological effects of microwaves in the hyperfrequency range, 9.4 GHz, 17 GHz, and 70–75 GHz were investigated in bacteria and yeast. At power densities below 60 mW/cm2 and SAR values not exceeding 28 mW/g no...

    M. Dardalhon, D. Averbeck, A. J. Berteaud in Radiation and Environmental Biophysics (1981)

  12. No Access

    Article

    Lethality and “petite” mutation induced by the photoaddition of 8-methoxypsoralen in yeast

    The induction of lethal events and cytoplasmic “petite” mutations in random and synchronously dividing cultures of haploid and diploid cells of Saccharomyces cerevisiae was determined after treatment with 8-Metho...

    J. A. P. Henriques, R. Chanet, D. Averbeck… in Molecular and General Genetics MGG (1977)

  13. No Access

    Chapter and Conference Paper

    Repair of Damage Induced by Near Ultraviolet Light Plus Furocoumarin in Saccharomyces cerevisiae

    Furocoumarins such as psoralen and 8 methoxypsoralen (8-MOP) and some of their derivatives are photosensitizing agents. They are known to sensitize human and guinea pig skin to near ultraviolet (UV) light and ...

    D. Averbeck in Radiation and Cellular Control Processes (1976)

  14. No Access

    Article

    Structural specificity in the lethal and mutagenic activity of furocoumarins in yeast cells

    Using monofunctional (Angelicin) and bifunctional furocoumarins (Psoralen and 8 Methoxypsoralen) plus 365 nm light it is shown that both damages, the induced monoadducts and/or crosslinks in DNA, provoke letha...

    D. Averbeck, Prof. Prakash Chandra, R. K. Biswas in Radiation and Environmental Biophysics (1975)

  15. No Access

    Article

    Four radiation sensitive mutants of Saccharomyces

    Three not closely linked genes (r 1 s , r 2 s ...

    D. Averbeck, W. Laskowski, F. Eckardt… in Molecular and General Genetics MGG (1970)