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Article
Open AccessCarfilzomib–lenalidomide–dexamethasone vs lenalidomide–dexamethasone in relapsed multiple myeloma by previous treatment
Carfilzomib, a proteasome inhibitor, is approved as monotherapy and in combination with dexamethasone or lenalidomide–dexamethasone (Rd) for relapsed or refractory multiple myeloma. The approval of carfilzomib...
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Chapter and Conference Paper
Systematic Design of Prognostics and Health Management Solutions for Energy Applications
Nowadays, energy has become a key issue in all sectors of industry. Analytical tools in the prognostics and health management (PHM) area are needed to transform energy and related data into actionable informat...
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Article
Transfer of Natural Micro Structures to Bionic Lightweight Design Proposals
The abstraction of complex biological lightweight structure features into a producible technical component is a fundamental step within the transfer of design principles from nature to technical lightweight so...
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Article
Hydrology of the Jordan River Basin: Watershed Delineation, Precipitation and Evapotranspiration
The Jordan River Basin is shared between Lebanon, Syria, Israel, Jordan and Palestine; the waters of the River are a critical resource for the future water security of the co-riparians. Because of the politica...
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Article
Erratum: Risk of progression and survival in multiple myeloma relapsing after therapy with IMiDs and bortezomib: A multicenter international myeloma working group study
Correction to: Leukemia (2012) 26, 149–157; doi:10.1038/leu.2011.196 Since the publication of this paper, the authors have noticed that one of the author names in the appendix was incorrectly listed as Hareth ...
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Article
Management of treatment-emergent peripheral neuropathy in multiple myeloma
Peripheral neuropathy (PN) is one of the most important complications of multiple myeloma (MM) treatment. PN can be caused by MM itself, either by the effects of the monoclonal protein or in the form of radicu...
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Article
Risk of progression and survival in multiple myeloma relapsing after therapy with IMiDs and bortezomib: A multicenter international myeloma working group study
Promising new drugs are being evaluated for treatment of multiple myeloma (MM), but their impact should be measured against the expected outcome in patients failing current therapies. However, the natural hist...
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Article
Stem cell collection in patients with multiple myeloma: impact of induction therapy and mobilization regimen
Lenalidomide is an active treatment for multiple myeloma (MM) and is increasingly used as part of the initial treatment of this disease. Recent reports have suggested decreases in the number of CD34+ cells col...
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Article
International myeloma working group consensus statement and guidelines regarding the current role of imaging techniques in the diagnosis and monitoring of multiple Myeloma
Several imaging technologies are used for the diagnosis and management of patients with multiple myeloma (MM). Conventional radiography, computed tomography (CT), magnetic resonance imaging (MRI) and nuclear m...
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Article
Rapid detection of Staphylococcus aureus bacteremia and methicillin resistance by real-time PCR in whole blood samples
We prospectively evaluated a real-time polymerase chain reaction (PCR) approach for the rapid diagnosis of Staphylococcus aureus bacteremia and presence of the mecA gene in 902 blood samples from 468 infectious e...
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Article
Erratum: The role of vertebral augmentation in multiple myeloma: International Myeloma Working Group Consensus Statement
Correction to: Leukemia advance online publication, 29 May 2008; doi:10.1038/leu.2008.127 Since the publication of the above paper, the authors have noticed an error in Dr Randall's name. The correct name is s...
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Article
The role of vertebral augmentation in multiple myeloma: International Myeloma Working Group Consensus Statement
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Article
Blood pressure control in a diabetic population assessed by computer review
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Article
A Graph Theoretic Approach to Strong Monotonicity with respect to Polyhedral Cones
Consider the flow ϕt for the system of differential equations \(\dot x\left( t \right) = f\left( x \right)\) , xεΩ, ...
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Article
Global stability of complex balanced mechanisms
We prove that the ω‐limit set of any solution of a complex balanced chemical reaction mechanism contains either a unique, positive complex balanced equilibrium point, or boundary complex balanced equilibrium p...
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Article
Melphalan plus total body irradiation (MEL-TBI) or cyclophosphamide (MEL-CY) as a conditioning regimen with second autotransplant in responding patients with myeloma is inferior compared to historical controls receiving tandem transplants with melphalan alone
The role of more intense conditioning for second transplant was evaluated in myeloma patients achieving at least partial remission (PR) after first transplant with melphalan at 200 mg/m2. Forty-three patients rec...
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Article
Patients with multiple myeloma may safely undergo autologous transplantation despite ongoing RSV infection and no ribavirin therapy
Respiratory syncytial virus (RSV) has been reported as a cause of death among autologous peripheral blood stem cell (ASCT) and marrow recipients and recommendations for therapy with aerosolized ribavirin plus ...
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Article
Collection of peripheral blood stem cells after a preceding autograft: unfavorable effect of prior interferon-α therapy
Eighty-eight previously autografted (78 transplanted twice and 10 once) myeloma patients who had no cryopreserved stem cells available for possible future use received G-CSF for mobilization of stem cells. One...
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Article
Salvage autologous or allogeneic transplantation for multiple myeloma refractory to or relapsing after a first-line autograft?
Forty-two patients allografted for multiple myeloma after not having attained at least a partial remission (n = 19) or after having experienced disease progression (n = 23) following one autograft were compared w...
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Article
High-dose chemotherapy with carboplatin, cyclophosphamide and etoposide and autologous transplantation for multiple myeloma relapsing after a previous transplant
Eighteen extensively pre-treated patients (35–73 years, median 46) with relapsed multiple myeloma received salvage chemotherapy with 6 g/m2 cyclophosphamide, 800 mg/m2 carboplatin, and 1800 mg/m2 etoposide (CCV) ...