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  1. Article

    Open Access

    Evidence for genetic heterogeneity between clinical subtypes of bipolar disorder

    We performed a genome-wide association study of 6447 bipolar disorder (BD) cases and 12 639 controls from the International Cohort Collection for Bipolar Disorder (ICCBD). Meta-analysis was performed with prio...

    A W Charney, D M Ruderfer, E A Stahl, J L Moran, K Chambert… in Translational Psychiatry (2017)

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  2. Article

    Open Access

    Insights into psychosis risk from leukocyte microRNA expression

    Dysregulation of immune system functions has been implicated in schizophrenia, suggesting that immune cells may be involved in the development of the disorder. With the goal of a biomarker assay for psychosis ...

    C D Jeffries, D O Perkins, S D Chandler, T Stark, E Yeo… in Translational Psychiatry (2016)

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  3. No Access

    Article

    Genome-wide pharmacogenomic analysis of response to treatment with antipsychotics

    Schizophrenia is an often devastating neuropsychiatric illness. Understanding the genetic variation affecting response to antipsychotics is important to develop novel diagnostic tests to match individual schiz...

    J L McClay, D E Adkins, K Åberg, S Stroup, D O Perkins… in Molecular Psychiatry (2011)

  4. No Access

    Article

    Expanding the ‘central dogma’: the regulatory role of nonprotein coding genes and implications for the genetic liability to schizophrenia

    It is now evident that nonprotein coding RNA (ncRNA) plays a critical role in regulating the timing and rate of protein translation. The potential importance of ncRNAs is suggested by the observation that the ...

    D O Perkins, C Jeffries, P Sullivan in Molecular Psychiatry (2005)