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  1. Article

    Open Access

    Red blood cell distribution width is associated with sarcopenia risk in early-stage non-small cell lung cancer

    Sarcopenia has received increasing attention in non-small cell lung cancer (NSCLC). Red blood cell distribution width (RDW) is a significant component of the complete blood count and indicates the heterogeneit...

    Qing-chun Jia, Ling Qin, Ye Niu, Le Liu, **-** Liu, Shi-di Miao in BMC Cancer (2024)

  2. No Access

    Article

    Capsaicin functions as a selective degrader of STAT3 to enhance host resistance to viral infection

    Although STAT3 has been reported as a negative regulator of type I interferon (IFN) signaling, the effects of pharmacologically inhibiting STAT3 on innate antiviral immunity are not well known. Capsaicin, appr...

    Mei-qi Zhang, **n Jia, Cui-qin Cheng, Yu-xi Wang, Yi-ying Li in Acta Pharmacologica Sinica (2023)

  3. No Access

    Article

    Scoparone suppresses mitophagy-mediated NLRP3 inflammasome activation in inflammatory diseases

    Recent evidence shows that targeting NLRP3 inflammasome activation is an important means to treat inflammasome-driven diseases. Scoparone, a natural compound isolated from the Chinese herb Artemisia capillaris Th...

    Wan-di Feng, Yao Wang, Tong Luo, **n Jia, Cui-qin Cheng in Acta Pharmacologica Sinica (2023)

  4. No Access

    Article

    A phase III randomized, double-blind, placebo-controlled trial of the denosumab biosimilar QL1206 in postmenopausal Chinese women with osteoporosis and high fracture risk

    The current study evaluated the efficacy and safety of a denosumab biosimilar, QL1206 (60 mg), compared to placebo in postmenopausal Chinese women with osteoporosis and high fracture risk. At 31 study centers ...

    Hao Zhang, Jie-mei Gu, Ai-jun Chao, Qun Cheng, Dong-hui Teng in Acta Pharmacologica Sinica (2023)

  5. Article

    Open Access

    Investigation of urine metabolome of BALB/c mouse infected with an avirulent strain of Toxoplasma gondii

    The protozoan parasite Toxoplasma gondii is a major concern for human and animal health. Although the metabolic understanding of toxoplasmosis has increased in recent years, the analysis of metabolic alterations ...

    Chun-Xue Zhou, Ling-Yu Li, Cui-Qin Huang, Xu-Dong Guo, Xu-Dian An in Parasites & Vectors (2022)

  6. No Access

    Article

    MK2206 attenuates atherosclerosis by inhibiting lipid accumulation, cell migration, proliferation, and inflammation

    Cardiovascular disease is a common comorbidity in patients with cancer, and the main leading cause of noncancer-related deaths in cancer survivors. Considering that current antitumor drugs usually induce cardi...

    Ya-qin Tang, Zhi-wei Li, Yu-fan Feng, Hong-qin Yang in Acta Pharmacologica Sinica (2022)

  7. Article

    Open Access

    Retraction Note: A positive feedback loop consisting of C12orf59/NF-κB/CDH11 promotes gastric cancer invasion and metastasis

    This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s13046-019-1114-2.

    Zhang Jia-**ng, He Wei-Ling, Feng Zi-Hao in Journal of Experimental & Clinical Cancer … (2021)

  8. Article

    Open Access

    Differential metabolism-associated gene expression of duck pancreatic cells in response to two strains of duck hepatitis A virus type 1

    Several outbreaks of duck hepatitis A virus type 1 (DHAV-1), which were characterized by yellow coloration and hemorrhage in pancreatic tissues, have occurred in China. The causative agent is called pancreatit...

    Zhen Chen, Shao-hua Shi, Yu Huang, Cui-qin Huang, Rong-chang Liu in Archives of Virology (2021)

  9. No Access

    Article

    Prevalence, Molecular Characterization and Risk Factors of Blastocystis sp. from Farmed Pigs in Yunnan Province, Southwestern China

    Blastocystis is an enteral eukaryote that omnipresent existence in animals and humans global. The objective of the current study investigated the frequency and subtypes to evaluate risk factors for Blastocystis i...

    Jian Qiang Han, Zhao Li, Yang Zou, Li Hua Pu, **n Quan Zhu in Acta Parasitologica (2020)

  10. Article

    Open Access

    Value of AFP and PIVKA-II in diagnosis of HBV-related hepatocellular carcinoma and prediction of vascular invasion and tumor differentiation

    To explore the value of alpha fetoprotein (AFP) and protein induced by vitamin K absence or antagonist-II (PIVKA-II) in diagnosis of HBV-related hepatocellular carcinoma (HCC) and their relationship with vascu...

    Yuan-Quan Si, **u-Qin Wang, Gang Fan, Chang-Yin Wang in Infectious Agents and Cancer (2020)

  11. Article

    Antibody responses to SARS-CoV-2 in patients with COVID-19

    We report acute antibody responses to SARS-CoV-2 in 285 patients with COVID-19. Within 19 days after symptom onset, 100% of patients tested positive for antiviral immunoglobulin-G (IgG). Seroconversion for IgG...

    Quan-**n Long, Bai-Zhong Liu, Hai-Jun Deng, Gui-Cheng Wu, Kun Deng in Nature Medicine (2020)

  12. Article

    Open Access

    Gut microbiota-derived indole 3-propionic acid protects against radiation toxicity via retaining acyl-CoA-binding protein

    We have proved fecal microbiota transplantation (FMT) is an efficacious remedy to mitigate acute radiation syndrome (ARS); however, the mechanisms remain incompletely characterized. Here, we aimed to tease apa...

    Hui-wen **ao, Ming Cui, Yuan Li, Jia-li Dong, Shu-qin Zhang, Chang-chun Zhu in Microbiome (2020)

  13. Article

    Open Access

    Dectin-1/Syk signaling triggers neuroinflammation after ischemic stroke in mice

    Dendritic cell-associated C-type lectin-1 (Dectin-1) receptor has been reported to be involved in neuroinflammation in Alzheimer’s disease and traumatic brain injury. The present study was designed to investig...

    **n-Chun Ye, Qi Hao, Wei-**g Ma, Qiu-Chen Zhao in Journal of Neuroinflammation (2020)

  14. Article

    Open Access

    RETRACTED ARTICLE: A positive feedback loop consisting of C12orf59/NF-κB/CDH11 promotes gastric cancer invasion and metastasis

    Metastasis remains the main cause of cancer-related death for gastric cancer (GC) patients, but the mechanisms are poorly understood. Using The Cancer Genome Atlas (TCGA) data base and bioinformatics analyses,...

    Jia-**ng Zhang, Wei-Ling He, Zi-Hao Feng in Journal of Experimental & Clinical Cancer … (2019)

  15. No Access

    Article

    Prevalence, genotypes, and risk factors of Enterocytozoon bieneusi in Asiatic black bear (Ursus thibetanus) in Yunnan Province, Southwestern China

    Microsporidiosis is an important zoonotic disease, even leading to severe diarrhea. However, no information about prevalence and genotypes of Enterocytozoon bieneusi infection in Asiatic black bears in southweste...

    Jie Wu, Jian-Qiang Han, Lian-Qin Shi, Yang Zou, Zhao Li in Parasitology Research (2018)

  16. Article

    Open Access

    26th Annual Computational Neuroscience Meeting (CNS*2017): Part 2

    Leonid L. Rubchinsky, Sungwoo Ahn, Wouter Klijn, Ben Cumming in BMC Neuroscience (2017)

  17. Article

    Open Access

    Genomic analysis of snub-nosed monkeys (Rhinopithecus) identifies genes and processes related to high-altitude adaptation

    Li Yu, Ya-** Zhang, Chung-I Wu and colleagues report the de novo genome of the black snub-nosed monkey Rhinopithecus bieti and the genomic sequences of four other Rhinopithecus species, including three high-alt...

    Li Yu, Guo-Dong Wang, Jue Ruan, Yong-Bin Chen, Cui-** Yang, Xue Cao in Nature Genetics (2016)

  18. Article

    Open Access

    Decreased expression of Sushi Domain Containing 2 correlates to progressive features in patients with hepatocellular carcinoma

    Sushi Domain Containing 2 (SUSD2) has been identified as a regulator of colon and breast cancer. Increasing evidence suggests that SUSD2 plays a key role in tumorigenesis. However, the SUSD2 expression status ...

    **n-rui Liu, Cui-xia Cai, Li-min Luo, Wen-Ling Zheng, Rong Shi in Cancer Cell International (2016)

  19. No Access

    Article

    Reducing the oxidative stress mediates the cardioprotection of bicyclol against ischemia-reperfusion injury in rats

    To investigate the beneficial effect of bicyclol on rat hearts subjected to ischemia-reperfusion (IR) injuries and its possible mechanism.

    Jie Cui, Zhi Li, Ling-bo Qian, Qin Gao in Journal of Zhejiang University SCIENCE B (2013)

  20. Article

    Open Access

    Use of immuno-dominant epitope derived from genotype 4 as a diagnostic reagent for detecting the antibodies against Hepatitis E Virus

    Despite the genotype 4 has become the dominant cause of hepatitis E disease in China, none antigen derived from genotype 4 of hepatitis E virus (HEV) was used in current commercial anti-HEV immunoassay, and th...

    **u Bing-shui, Feng **ao-yan, He **g, Chen Kun, Liu **g, Dai Zhen-hua in Virology Journal (2013)

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