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Article
Single-cell multi-omics sequencing of human spermatogenesis reveals a DNA demethylation event associated with male meiotic recombination
Human spermatogenesis is a highly ordered process; however, the roles of DNA methylation and chromatin accessibility in this process remain largely unknown. Here by simultaneously investigating the chromatin a...
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Article
Titanosilicate mesoporous materials with adjustable textural properties for catalyzing the acetalization reaction of biomass derived furfural and n-propanol
Titanosilicate mesoporous materials (TiSi-MMs) with adjustable textural properties were synthesized by the sol-gel method. Tetraethyl orthosilicate (TEOS) was used as Si source, while tetraethyl orthotitanate ...
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Article
Open AccessTargeting APLN/APJ restores blood-testis barrier and improves spermatogenesis in murine and human diabetic models
Type 2 diabetes mellitus is one of the most prevalent metabolic diseases presenting with systemic pathologies, including reproductive disorders in male diabetic patients. However, the molecular mechanisms that...
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Article
Open AccessCell-fate transition and determination analysis of mouse male germ cells throughout development
Mammalian male germ cell development is a stepwise cell-fate transition process; however, the full-term developmental profile of male germ cells remains undefined. Here, by interrogating the high-precision tra...
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Article
A span-based model for aspect terms extraction and aspect sentiment classification
Sentiment analysis is a field of natural language processing, which is used to identify and extract opinions and attitudes from text. Aspect-based sentiment analysis aims to extract aspect terms and predict se...
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Chapter and Conference Paper
A PSO-Based Virtual Network Map** Algorithm with Crossover Operator
Virtual network map** (VNM) is a crucial technology for network virtualization to allocate network resource. One of the major challenges for virtual network map** is the efficient allocation of substrate r...
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Article
Open AccessAutotetraploid cell Line induced by SP600125 from crucian carp and its developmental potentiality
Polyploidy has many advantages over diploidy, such as rapid growth, sterility and disease resistance and has been extensively applied in agriculture and aquaculture. Though generation of new polyploids via pol...
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Article
Open AccessExcess salt exacerbates blood-brain barrier disruption via a p38/MAPK/SGK1-dependent pathway in permanent cerebral ischemia
High salt diet (HSD) is one of the most important risk factors that contribute to many vascular diseases including ischemic stroke. One proposed mechanism underlying the disruption of blood-brain barrier (BBB)...
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Article
Morphometric Characterization and Reconstruction Effect Among Lunar Impact Craters
Impact craters on the lunar surface have a variety of morphometric characteristics that are very useful in understanding the evolutionary history of lunar landscape morphologies. Based on digital elevation mo...
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Chapter and Conference Paper
Repeatable Optimization Algorithm Based Discrete PSO for Virtual Network Embedding
Aiming at reducing the link load and improving substrate network resource utilization ratio, we model the virtual network embedding (VNE) problem as an integer linear programming and present a discrete particl...
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Chapter and Conference Paper
Utility-Driven Share Scheduling Algorithm in Hadoop
Job scheduling in hadoop is a hot topic, however, current research mainly focuses on the time optimization in scheduling. With the trend of providing hadoop as a service to the public or specified groups, more...
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Chapter and Conference Paper
Virtual Network Embedding Algorithm Based Connective Degree and Comprehensive Capacity
Network virtualization allows multiple virtual networks to coexist on a shared physical substrate infrastructure. As far as possible to support more virtual networks on a shared substrate network, efficient ph...
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Chapter and Conference Paper
Game-Based Scheduling Algorithm to Achieve Optimize Profit in MapReduce Environment
MapReduce is a programming model and an associated implementation for processing and generating large data sets. Providing MapReduce as a service is the development future trend. By leveraging the game theory,...
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Article
Automatic extraction of lunar impact craters from Chang’E-1 satellite photographs
The distribution characteristics of the impact craters can provide a large amount of information on impact history and the lunar evolution process. In this research, based on the digital elevation model (DEM) ...
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Chapter and Conference Paper
MRKDSBC: A Distributed Background Modeling Algorithm Based on MapReduce
Video surveillance is a widely used technology. Moving object detection is the most important content of video surveillance. Background modeling is an important method in moving object detection. However, back...
