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Article
Open AccessRisk of second primary cancer among women in the Kaiser Permanente Breast Cancer Survivors Cohort
Breast cancer survivors are living longer due to early detection and advances in treatment and are at increased risk for second primary cancers. Comprehensive evaluation of second cancer risk among patients tr...
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Article
Open AccessShort-term changes in ultrasound tomography measures of breast density and treatment-associated endocrine symptoms after tamoxifen therapy
Although breast density decline with tamoxifen therapy is associated with greater therapeutic benefit, limited data suggest that endocrine symptoms may also be associated with improved breast cancer outcomes. ...
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Article
Correction to: The influence of treatment on hormone receptor subgroups and breast cancer-specific mortality within US integrated healthcare systems
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Article
The influence of treatment on hormone receptor subgroups and breast cancer-specific mortality within US integrated healthcare systems
Estrogen receptor (ER) + /progesterone receptor (PR) – or ER−/PR + breast cancer prognosis has not been well-described outside of clinical trials. We evaluated the relationship between ER/PR (ER + /PR−, ER−/PR...
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Article
Endocrine therapy initiation among women with stage I–III invasive, hormone receptor-positive breast cancer from 2001–2016
This retrospective cohort study examined patterns of endocrine therapy initiation over time and by demographic, tumor, and treatment characteristics.
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Article
Open AccessTrends in heart disease mortality among breast cancer survivors in the US, 1975–2017
Heart disease is a significant concern among breast cancer survivors, in part due to cardiotoxic treatments including chemotherapy and radiotherapy. Long-term trends in heart disease mortality have not been we...
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Article
Risk factors for contralateral breast cancer in postmenopausal breast cancer survivors in the NIH-AARP Diet and Health Study
The role of established breast cancer risk factors and clinical characteristics of the first breast cancer in the development of contralateral breast cancer (CBC) among postmenopausal women is unclear.
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Article
Open AccessRisk of contralateral breast cancer according to first breast cancer characteristics among women in the USA, 1992–2016
Estimates of contralateral breast cancer (CBC) risk in the modern treatment era by year of diagnosis and characteristics of the first breast cancer are needed to assess the impact of recent advances in breast ...
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Article
The estrogen receptor-alpha S118P variant does not affect breast cancer incidence or response to endocrine therapies
Estrogen receptor-alpha (ER) is a therapeutic target of ER-positive (ER+) breast cancers. Although ER signaling is complex, many mediators of this pathway have been identified. Specifically, phosphorylation of...
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Article
Open AccessEvaluation of osteopenia and osteoporosis in younger breast cancer survivors compared with cancer-free women: a prospective cohort study
Osteoporosis, an indicator of significant bone loss, has been consistently reported among older breast cancer survivors. Data are limited on the incidence of osteopenia, an earlier indicator of bone loss, and ...
