5 Result(s)
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Cody Ashby
Life Sciences
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Article
Open AccessFiNGS: high quality somatic mutations using filters for next generation sequencing
Somatic variant callers are used to find mutations in sequencing data from cancer samples. They are very sensitive and have high recall, but also may produce low precision data with a large proportion of false...
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Article
Open AccessTarPan: an easily adaptable targeted sequencing panel viewer for research and clinical use
The study of cancer genomics continually matures as the number of patient samples sequenced increases. As more data is generated, oncogenic drivers for specific cancer types are discovered along with their ass...
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Article
Open AccessEnhancing cancer clonality analysis with integrative genomics
It is understood that cancer is a clonal disease initiated by a single cell, and that metastasis, which is the spread of cancer from the primary site, is also initiated by a single cell. The seemingly natural ...
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Article
Open AccessBridger: a new framework for de novo transcriptome assembly using RNA-seq data
We present a new de novo transcriptome assembler, Bridger, which takes advantage of techniques employed in Cufflinks to overcome limitations of the existing de novo assemblers. When tested on dog, human, and mous...
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Article
Open AccessNew enumeration algorithm for protein structure comparison and classification
Protein structure comparison and classification is an effective method for exploring protein structure-function relations. This problem is computationally challenging. Many different computational approaches f...
