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Open AccessConjugation of HIV-1 envelope to hepatitis B surface antigen alters vaccine responses in rhesus macaques
An effective HIV-1 vaccine remains a critical unmet need for ending the AIDS epidemic. Vaccine trials conducted to date have suggested the need to increase the durability and functionality of vaccine-elicited ...
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Article
Racial Differences in Over-the-Counter Non-steroidal Anti-inflammatory Drug Use Among Individuals at Risk of Adverse Cardiovascular Events
Black Americans are disproportionately affected by adverse cardiovascular events (ACEs). Over-the-counter (OTC) non-steroidal anti-inflammatory drugs (NSAIDs) confer increased risk for ACEs, yet racial differe...
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Article
Open AccessPsychosocial determinants of cardiovascular events among black Americans with chronic kidney disease or associated risk factors in the Jackson heart study
Individuals with chronic kidney disease (CKD), hypertension (HTN), or diabetes mellitus (DM) are at increased risk for cardiovascular disease (CVD). The extent to which psychosocial factors are associated with...
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Article
Preliminary evidence of effects of potassium chloride on a metabolomic path to diabetes and cardiovascular disease
Low potassium intake can affect cardiovascular disease (CVD) risk and cardiometabolic risk factors.
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Open AccessAssociation of functional and structural social support with chronic kidney disease among African Americans: the Jackson Heart Study
There is limited evidence on the relationship between social support and renal outcomes in African Americans. We sought to determine the association of social support with prevalent chronic kidney disease (CKD...
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Open AccessLow use of routine medical care among African Americans with high CKD risk: the Jackson Heart Study
Use of routine medical care (RMC) is advocated to address ethnic/racial disparities in chronic kidney disease (CKD) risks, but use is less frequent among African Americans. Factors associated with low RMC use ...
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Article
A Powerful Test for SNP Effects on Multivariate Binary Outcomes Using Kernel Machine Regression
Evaluating multiple binary outcomes is common in genetic studies of complex diseases. These outcomes are often correlated because they are collected from the same individual and they may share common marker ef...
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Improving on the diagnostic characteristics of echocardiography for pulmonary hypertension
This retrospective study evaluated the diagnostic characteristics of a combination of echocardiographic parameters for pulmonary hypertension (PH). Right ventricular systolic pressure (RVSP) estimation by echo...
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Open AccessClinical and echocardiographic predictors of mortality in acute pulmonary embolism
The aim of this study was to evaluate the utility of adding quantitative assessments of cardiac function from echocardiography to clinical factors in predicting the outcome of patients with acute pulmonary emb...