6 Result(s)

Article

Author Correction: Bridging of host-microbiota tryptophan partitioning by the serotonin pathway in fungal pneumonia

Giorgia Renga, Fiorella D’Onofrio, Marilena Pariano… in Nature Communications (2024)

Article

Dual species sphingosine-1-phosphate lyase inhibitors to combine antifungal and anti-inflammatory activities in cystic fibrosis: a feasibility study

Cystic fibrosis (CF) is an autosomal recessive disorder characterized by respiratory failure due to a vicious cycle of defective Cystic Fibrosis Transmembrane conductance Regulator (CFTR) function, chronic inf...

Barbara Cellini, Gioena Pampalone, Emidio Camaioni, Marilena Pariano… in Scientific Reports (2023)

Article

Bridging of host-microbiota tryptophan partitioning by the serotonin pathway in fungal pneumonia

The aromatic amino acid L-tryptophan (Trp) is essentially metabolized along the host and microbial pathways. While much is known about the role played by downstream metabolites of each pathways in intestinal h...

Giorgia Renga, Fiorella D’Onofrio, Marilena Pariano… in Nature Communications (2023)

Article

The prion protein family member Shadoo induces spontaneous ionic currents in cultured cells

Some mutant forms of the cellular prion protein (PrP^C) carrying artificial deletions or point mutations associated with familial human prion diseases are capable of inducing spontaneous ionic currents across the ...

Antal Nyeste, Claudia Stincardini, Petra Bencsura, Milica Cerovic… in Scientific Reports (2016)

Article

A cationic tetrapyrrole inhibits toxic activities of the cellular prion protein

Prion diseases are rare neurodegenerative conditions associated with the conformational conversion of the cellular prion protein (PrP^C) into PrP^Sc, a self-replicating isoform (prion) that accumulates in the centr...

Tania Massignan, Sara Cimini, Claudia Stincardini, Milica Cerovic… in Scientific Reports (2016)