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Article
Open AccessAdhesion energy controls lipid binding-mediated endocytosis
Several bacterial toxins and viruses can deform membranes through multivalent binding to lipids for clathrin-independent endocytosis. However, it remains unclear, how membrane deformation and endocytic interna...
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Article
Open AccessCanonical and non-canonical integrin-based adhesions dynamically interconvert
Adhesions are critical for anchoring cells in their environment, as signaling platforms and for cell migration. In line with these diverse functions different types of cell-matrix adhesions have been described...
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Article
Open AccessThree-dimensional structured illumination microscopy with enhanced axial resolution
The axial resolution of three-dimensional structured illumination microscopy (3D SIM) is limited to ∼300 nm. Here we present two distinct, complementary methods to improve axial resolution in 3D SIM with minim...
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Article
Open AccessThe molecular organization of differentially curved caveolae indicates bendable structural units at the plasma membrane
Caveolae are small coated plasma membrane invaginations with diverse functions. Caveolae undergo curvature changes. Yet, it is unclear which proteins regulate this process. To address this gap, we develop a co...
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Article
Structure and assembly of the mitochondrial membrane remodelling GTPase Mgm1
Balanced fusion and fission are key for the proper function and physiology of mitochondria1,2. Remodelling of the mitochondrial inner membrane is mediated by the dynamin-like protein mitochondrial genome maintena...
