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Article
Open AccessEvaluation of randomized controlled trials: a primer and tutorial for mental health researchers
Considered one of the highest levels of evidence, results of randomized controlled trials (RCTs) remain an essential building block in mental health research. They are frequently used to confirm that an interv...
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Article
Open AccessEvaluating a multimodal, clinical and work-directed intervention (RTW-PIA) to support sustainable return to work among employees with mental disorders: study protocol of a multicentre, randomised controlled trial
Mental disorders (MDs) are one of the leading causes for workforce sickness absence and disability worldwide. The burden, costs and challenges are enormous for the individuals concerned, employers and society ...
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Prävention
Die Global Burden of Disease Studie aus dem Jahr 2017 schätzt, dass über 91 % der Todesfälle und fast 87 % der „disability-adjusted life years“ in der EU auf nicht-übertragbare Krankheiten zurückzuführen sind....
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Article
Open AccessSystematic review of economic evaluations for internet- and mobile-based interventions for mental health problems
In view of the staggering disease and economic burden of mental disorders, internet and mobile-based interventions (IMIs) targeting mental disorders have often been touted to be cost-effective; however, availa...
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Article
Open AccessClinical and cost-effectiveness of guided internet-based interventions in the indicated prevention of depression in green professions (PROD-A): study protocol of a 36-month follow-up pragmatic randomized controlled trial
People in green professions are exposed to a variety of risk factors, which could possibly enhance the development of depression. Amongst possible prevention approaches, internet- and mobile-based intervention...
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Article
Open AccessEvaluating the efficacy and cost-effectiveness of web-based indicated prevention of major depression: design of a randomised controlled trial
Major depressive disorder (MDD) imposes a considerable disease burden on individuals and societies. Web-based interventions have shown to be effective in reducing depressive symptom severity. However, it is no...
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Article
Open AccessGET.ON Mood Enhancer: efficacy of Internet-based guided self-help compared to psychoeducation for depression: an investigator-blinded randomised controlled trial
Major depressive disorder (MDD) imposes a considerable disease burden on individuals and societies. A large number of randomised controlled trials (RCTs) have shown the efficacy of Internet-based guided self-h...
