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Article
Multigram synthesis of 1-alkylamido phospholipids
Phospholipids containing a 1-alkylamido linkage have shown promisingin vitro neoplastic cell growth inhibitory properties and anti-human immunodeficiency viral activity. We have synthesized a series of alkylamido...
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Article
Synthesis and Biological Evaluation of Ether-Linked Derivatives of Phosphatidylinositol
The synthesis of two novel glycero-3-phosphoinositol ether lipid analogues, rac-l-O-octadecyl-2-O methylglycero-3-phospho-myo-inositol 6 (an ether lipid analogue of rac-l-O-octadecyl-2-O-methylglycero-3-phosphoch...
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Article
Neoplastic cell inhibition with new ether lipid analogs
Bioactive phospholipid analogs of platelet-activating factor (PAF) represent a new approach to cancer chemotherapy. Various modifications of the basic structure of PAF lead to different ether lipid (EL) analog...
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Article
Metabolism of alkyl glyceryl ethers in the rat
The metabolism of14C- and3H-labeled alkyl glyceryl ethers after intraperitoneal injections was examined in the liver and intestine of the rat. Additionally, in vitro experiments were conducted with intestinal hom...
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Article
Lipid droplets and glyceryl ether diesters in ehrlich ascites cells grown in tissue culture
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Article
The synthesis of14C- and3H-labeled glycerol ethers
The racemic14C-and3H-labeled alpha and beta derivatives of octadecyl glycerol ether (batyl alcohol) and of hexadecyl glycerol ether (chimyl alcohol) of high specific activity were synthesized by treating the appr...
