Handbook of Lipid Research
Volume 1 / 1978 to Volume 8 / 1996
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Article
The impact of patient navigation on the delivery of diagnostic breast cancer care in the National Patient Navigation Research Program: a prospective meta-analysis
Patient navigation is emerging as a standard in breast cancer care delivery, yet multi-site data on the impact of navigation at reducing delays along the continuum of care are lacking. The purpose of this stud...
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Chapter
Seismic Detection and Quantification of Gas Hydrates using Rock Physics and Inversion
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Book Series
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Book
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Chapter
Biosynthesis of Platelet Activating Factor and Related Acetylated Lipids
Platelet-activating factor (PAF) is synthesized by either de novo or remodeling enzymes (Snyder, 1995a,b). The remodeling of a preexisting membrane phospholipid, 1-alkyl-2-acyl-sn-glycero-3-phosphocholine (alkyla...
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Chapter
Biosynthesis of Platelet-Activating Factor and Enzyme Inhibitors
Platelet-activating factor (PAF) is known to be synthesized by either a remodeling or de novo pathway. The enzymes responsible have been extensively studied by a number of laboratories. All evidence indicates ...
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Metabolic processing of PAF
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Article
Molecular species of sphingomyelin in sphingomyelinase-sensitive and sphingomyelinase-resistant pools of HL-60 cells
This study of sphingomyelin molecular species in undifferentiated and differentiated (granulocytic form) HL-60 cells demonstrated only minor differences in the distribution of species between the sphingomyelin...
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Article
Chemical synthesis and physiological activity of sulfonium analogues of platelet activating factor
Phosphatidylsulfocholine (PSC), the sulfonium analogue of phosphatidylcholine (PC), occurs naturally in some diatoms. The replacement of the −N+(CH3)3 group by a −S+(CH3)2 results in an increase in the polar head...
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Article
Dietary supplementation with ether-linked lipids and tissue lipid composition
The goal of this investigation was to determine the effect of an alkylglycerol dietary supplement on the lipid composition of several major organs. Lipids from kidney, liver, and lung tissues of rats on a labo...
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Chapter
Introduction Historical Aspects of Alkyl Lipids and Their Biologically Active Forms (Ether Lipids, Platelet-Activating Factor, and Antihypertensive Renal Lipids)
This introduction reviews highlights of key historical developments that have occurred in research with alkyl ether glycerolipids, platelet-activating factor (PAF), and a group of renal antihypertensive lipids...
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Chapter
Chromatographic Analyses of Ether-Linked Lipids Involved in PAF Metabolism
A number of chromatographic separations were essential in elucidating the structure of l-alkyl-2-acetyl-sn-glycero-3-phosphocholine [(alkylacetyl-GPC) platelet activating factor (PAF)] (Benveniste et al., 1979; B...
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Chapter
Enzymatic Pathways for Platelet-Activating Factor, Related Alkyl Glycerolipids, and Their Precursors
The purpose of this chapter is to provide a succinct overview of the enzymatic reaction steps for alkyl glycerolipids and lipid precursors affiliated with the biosynthesis and catabolism of platelet-activating...
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Chapter
Ether-Linked Glycerolipids and Their Bioactive Species:Enzymes and Metabolic Regulation
The pioneering studies of those scientists who first discovered (1915–1924) and ultimately identified the precise nature of the chemical structure of the alkyl and alk-l-enyl (plasmalogens) linkages in glycero...
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Article
Phase transition of an unnatural analog of phosphatidylcholine: Phosphatidyl-N-isopropylethanolamine
The phase-transition temperature, of an aqueous dispersion of dipalmitoyl phosphatidyl-N-isopropylethanolamine was determined was determined usingtrans-parinaric acid as a fluorescent probe. Phosphatidyl-N-isopro...
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Chapter
Asymmetric Localization of Alkyldihydroxyacetone-P Synthase and Acyldihydroxyacetone-P Acyltransferase in Microsomal Vesicles
A number of investigations have made it clear that proteases and phospholipases can be used effectively in combination with detergents to determine the topographical distribution of microsomal membrane compone...
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Book
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Chapter
Microsomal Enzymes Involved in the Metabolism of Ether-Linked Glycerolipids and Their Precursors in Mammals
The pathway by which ether-linked glycerolipids are synthesized in animals remained obscure until 1968. Metabolic in vivo studies and structural analysis of alkyl-linked glycerolipids indicated that the alkyl cha...
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Article
Occurrence of ethanolamine- and choline-containing plasmalogens in adipose tissue
Analysis of phospholipids in porcine, bovine and rat adipose tissue revealed a relatively high level of plasmalogens (O-alk-1-enyl lipids). About 50% of the ethanolamine phospholipids in the pig and beef samples ...
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Article
Structural relationships between glycerides of pig serum and adipose tissue
Structural analyses have been performed on the triacylglycerols and phosphoglycerides isolated from adipose tissue, serum chylomicrons, and serum lipoproteins from pigs. The triacylglycerols from adipose tissu...
