Skip to main content

2 Result(s)

within Cihangir Duy Remove this filter

and

  1. No Access

    Article

    Histone demethylase LSD1 is required for germinal center formation and BCL6-driven lymphomagenesis

    Germinal center (GC) B cells feature repression of many gene enhancers to establish their characteristic transcriptome. Here we show that conditional deletion of Lsd1 in GCs significantly impaired GC formation, a...

    Katerina Hatzi, Huimin Geng, Ashley S. Doane, Cem Meydan… in Nature Immunology (2019)

  2. No Access

    Article

    BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR–ABL1 kinase inhibition

    Targeted cancer therapies are often associated with drug resistance, a phenomenon that has been observed with tyrosine kinase inhibitors (TKIs), widely used to treat leukaemia driven by BCR–ABL1 mutations. Markus...

    Cihangir Duy, Christian Hurtz, Seyedmehdi Shojaee, Leandro Cerchietti… in Nature (2011)