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    Isolation of C. elegans deletion mutants following ENU mutagenesis and thermostable restriction enzyme PCR screening

    The ability to generate null mutants is essential for studying gene function. Gene knockouts in Caenorhabditis elegans can be generated in a high throughput manner using chemical mutagenesis followed by polymeras...

    Chunyi George Huang, Peter Agre, Kevin Strange, Todd Lamitina in Molecular Biotechnology (2006)