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  1. Article

    Open Access

    Disturbance of neuron–microglia crosstalk mediated by GRP78 in Neuropsychiatric systemic lupus erythematosus mice

    Neuropsychiatric systemic lupus erythematosus (NPSLE) is a serious phenotype of systemic lupus erythematosus (SLE). The disturbance of neuron–microglia crosstalk is recently revealed in many neuropsychiatric d...

    **gyi Xu, Chunshu Yang, Siyuan Zeng, Xuejiao Wang… in Journal of Neuroinflammation (2023)

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  2. No Access

    Article

    Altered peripheral helper T cells in peripheral blood and muscle tissue of the patients with dermatomyositis

    Peripheral helper T (Tph) cells, phenotypically PD-1hiCXCR5-CD4+, are a recently identified Th cell subset that relates to several autoimmune diseases. Contrary to PD-1hiCXCR5+CD4+ follicular helper T (Tfh) ce...

    **aoyu Hou, Chunshu Yang, Meiyi Lin, Bailing Tian… in Clinical and Experimental Medicine (2021)

  3. No Access

    Article

    Urinary ferritin creatinine ratio, a potential biomarker for lupus nephritis activity

    Ferritin has gained increasing attention in systemic lupus erythematosus (SLE).This study aimed to investigate the clinical significance of urinary ferritin/creatinine ratio in lupus nephritis (LN).

    Lin Qi, **gyi Xu, Chunshu Yang, **aoyu Hou, **ting Yang in Clinical Rheumatology (2021)

  4. Article

    Open Access

    Lupus serum IgG induces microglia activation through Fc fragment dependent way and modulated by B-cell activating factor

    Neuropsychiatric manifestations are frequent in patients with systemic lupus erythematosus (SLE), yet the etiology and pathogenesis of brain damage in SLE remains unclear. Because the production of autoantibod...

    Chunshu Yang, **aoyu Hou, Qianhui Feng, Yingzhuo Li… in Journal of Translational Medicine (2019)

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  5. No Access

    Article

    Imbalance of circulating Tfr/Tfh ratio in patients with rheumatoid arthritis

    Follicular helper T(Tfh) cells and follicular regulatory T(Tfr) cells are critical for the development and maintenance of germinal center and humoral immune responses. Accumulating evidence has demonstrated th...

    **uzhen Wang, Chunshu Yang, Feng Xu, Lin Qi… in Clinical and Experimental Medicine (2019)

  6. No Access

    Article

    Serum level of DNase1l3 in patients with dermatomyositis/polymyositis, systemic lupus erythematosus and rheumatoid arthritis, and its association with disease activity

    DNase1l3 is an endonuclease to degrade the chromatin of apoptotic or necrotic cells. Serum DNase1l3 may fulfill the function of clearance of chromatin released into the circulation by dying cells, which can tr...

    Qi Zhao, Chunshu Yang, Jianing Wang, Yujia Li… in Clinical and Experimental Medicine (2017)