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Article
Open AccessMET fusions and splicing variants convergently define a subgroup of glioma sensitive to MET inhibitors
Our previous study has shown that PTPRZ1-MET (ZM) fusion is a viable target for MET inhibitors in gliomas. However, the diversity and prevalence of somatic MET alterations in diffuse gliomas are still elusive and...
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Article
Publisher Correction: Ventral striatal islands of Calleja neurons control grooming in mice
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Article
Circadian REV-ERBs repress E4bp4 to activate NAMPT-dependent NAD+ biosynthesis and sustain cardiac function
The heart is a highly metabolic organ that uses multiple energy sources to meet its demand for ATP production. Diurnal feeding–fasting cycles result in fluctuations in substrate availability, which, together w...
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Article
Open AccessEstablishment and validation of in-house cryopreserved CAR/TCR-T cell flow cytometry quality control
Chimeric antigen receptor (CAR) or T-cell receptor (TCR) engineered T-cell therapy has recently emerged as a promising adoptive immunotherapy approach for the treatment of hematologic malignancies and solid tu...
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Article
Ventral striatal islands of Calleja neurons control grooming in mice
The striatum comprises multiple subdivisions and neural circuits that differentially control motor output. The islands of Calleja (IC) contain clusters of densely packed granule cells situated in the ventral s...
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Article
Manganese-doped zinc oxide hollow balls for chemiresistive sensing of acetone vapors
Both pure and Mn(II)-doped ZnO hollow structures were synthesized by a solvothermal reaction, and their phase structures, morphologies and elemental composition were characterized. SEM and TEM observations sho...
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Protocol
Immunophenoty** of Acute Myeloid Leukemia
Immunophenoty** by multiparameter flow cytometry is a rapid and efficient technique to simultaneously assess and correlate multiple individual cell properties like size and internal complexity along with ant...
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Article
Homoharringtonine production by endophytic fungus isolated from Cephalotaxus hainanensis Li
Homoharringtonine (HHT), a natural plant alkaloid derived from Cephalotaxus, has demonstrated to have a broad antitumor activity and efficacy in treating human chronic myeloid leukemia. An alternative source is r...
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Article
Open AccessConstruction and analysis of dynamic transcription factor regulatory networks in the progression of glioma
The combinatorial cross-regulation of transcription factors (TFs) plays an important role in cellular identity and function; however, the dynamic regulation of TFs during glioma progression remains largely unk...
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Article
Molecular design and theoretical investigation on novel porphyrin derivatives for dye-sensitized solar cells
We report on a quantum-chemical study of the electronic and optical properties of a series of β, β′-edge-fused zinc porphyrin with different aromatic rings, in order to design efficient sensitizers for dye-sen...