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  1. Article

    Open Access

    Quantification of cardiac pum** mechanics in rats by using the elastance–resistance model based solely on the measured left ventricular pressure and cardiac output

    The cardiac pum** mechanics can be characterized by both the maximal systolic elastance (Emax) and theoretical maximum flow (Qmax), which are generated using an elastance–resistance model. The signals required ...

    Chih-Hsien Wang, Ru-Wen Chang, En-Ting Wu in Pflügers Archiv - European Journal of Phys… (2019)

  2. No Access

    Article

    Investigation of the self-assembly of CS and PCL copolymers with different molecular weights in water solution by coarse-grained molecular dynamics simulation

    Coarse-grained molecular dynamics (CGMD) simulation was employed to investigate how stable chondroitin sulfate-graft-polycaprolactone (CS-PCL, CP) copolymers self-assemble into micelles in an aqueous environment....

    Chun-Yi Chang, Shin-Pon Ju, Li-Fang Wang, Chien-Chia Chen in Journal of Molecular Modeling (2017)

  3. Article

    Open Access

    Determining arterial wave transit time from a single aortic pressure pulse in rats: vascular impulse response analysis

    Arterial wave transit time (τw) in the lower body circulation is an effective biomarker of cardiovascular risk that substantially affects systolic workload imposed on the heart. This study evaluated a method for ...

    Ru-Wen Chang, Chun-Yi Chang, Liang-Chuan Lai, Ming-Shiou Wu in Scientific Reports (2017)

  4. Article

    Open Access

    Systolic aortic pressure-time area is a useful index describing arterial wave properties in rats with diabetes

    The accurate measurement of arterial wave properties in terms of arterial wave transit time (τw) and wave reflection factor (Rf) requires simultaneous records of aortic pressure and flow signals. However, in clin...

    Ru-Wen Chang, Chun-Yi Chang, Ming-Shiou Wu, Hsi-Yu Yu, Jian-Ming Luo in Scientific Reports (2015)

  5. No Access

    Article

    Cross-Sectional and Longitudinal Associations of Categories of Physical Activities with Dimensions of Subjective Well-Being in Taiwanese Older Adults

    Physical activity takes place in different social contexts such as leisure, home, and work. However, the differential associations of these distinct categories of activity with aspects of well-being have rarel...

    Po-Wen Ku, Kenneth R. Fox, Chun-Yi Chang, Wen-Jung Sun in Social Indicators Research (2014)

  6. No Access

    Article

    Size and chain length effects on structural behaviors of biphenylcyclohexane-based liquid crystal nanoclusters by a coarse-grained model

    Size and chain length effects on structural behaviors of liquid crystal nanoclusters were examined by a coarse-grained model and the configurational-bias Monte Carlo (CBMC) simulation. The nanoclusters investi...

    Ming-Liang Liao, Shin-Pon Ju, Chun-Yi Chang, Wei-Lin Huang in Journal of Molecular Modeling (2012)