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Article
Glycinamide Facilitates Nanocomplex Formation and Functions Synergistically with Bone Morphogenetic Protein 2 to Promote Osteoblast Differentiation In Vitro and Bone Regeneration in a Mouse Calvarial Defect Model
This study aimed to identify glycine analogs conducive to the formation of cell-absorbable nanocomplexes, enhancing collagen synthesis and subsequent osteogenesis in combination with BMP2 for improved bone reg...
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Article
Open AccessSelf-assembling biomolecules for biosensor applications
Molecular self-assembly has received considerable attention in biomedical fields as a simple and effective method for develo** biomolecular nanostructures. Self-assembled nanostructures can exhibit high bind...
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Article
The Effect of the Mechanical Properties of the 3D Printed Gelatin/Hyaluronic Acid Scaffolds on hMSCs Differentiation Towards Chondrogenesis
Tissue engineering, including 3D bioprinting, holds great promise as a therapeutic tool for repairing cartilage defects. Mesenchymal stem cells have the potential to treat various fields due to their ability t...
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Article
Open AccessStem cell laden nano and micro collagen/PLGA bimodal fibrous patches for myocardial regeneration
Although the use of cardiac patches is still controversial, cardiac patch has the significance in the field of the tissue engineered cardiac regeneration because it overcomes several shortcomings of intra-myoc...
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Article
Open AccessThe effects of the molecular weights of hyaluronic acid on the immune responses
The molecular weight of hyaluronic acid (HyA) depends on the type of organ in the body. When HyA of the desired molecular weight is implanted into the human body for regeneration of damaged tissue, it is degra...
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Chapter
Chitosan for Tissue Engineering
Chitosan, a deacetylated chitin, is one of the few natural polymers similar to glycosaminoglycans (GAGs) widely distributed throughout connective tissues. It has been believed that the excellent biocompatibili...
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Chapter
3D Bioprinting Technologies for Tissue Engineering Applications
Three-dimensional (3D) printing (rapid prototy** or additive manufacturing) technologies have received significant attention in various fields over the past several decades. Tissue engineering applications o...
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Article
Low-Dose Ionizing γ-Radiation Promotes Proliferation of Human Mesenchymal Stem Cells and Maintains Their Stem Cell Characteristics
Mesenchymal stem cells (MSCs), which are multipotent and have self-renewal ability, support the regeneration of damaged normal tissue. A number of external stimuli promote migration of MSCs into peripheral blo...
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Article
In vitro evaluation of lysyl oxidase antibody conjugated nanoparticles
In this study, we prepared poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) conjugated to lysyl oxidase-inhibiting antibodies (LOXab) as an anticancer therapy in order to efficiently inhibit the growth of...
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Article
Open Access3-dimensional bioprinting for tissue engineering applications
The 3-dimensional (3D) printing technologies, referred to as additive manufacturing (AM) or rapid prototy** (RP), have acquired reputation over the past few years for art, architectural modeling, lightweight...
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Article
Cellular and soft tissue compatibility to high interconnectivity between pores of chitosan scaffold
In the field of tissue engineering and regenerative medicine, porosity, pore size, and pore interconnectivity of three-dimensional scaffolds affect cellular attachment, proliferation and, migration, and degree...
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Article
Generation of expression vectors for high-throughput functional analysis of target genes in Schizosaccharomyces pombe
An immediate challenge in the post-genomic era is to assign a biological functions to proteins unraveled by genome analysis. This report is based on studies conducted using Schizosaccharomyces pombe, a simple mod...
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Article
Fabrication of micro patterned fibronectin for studying adhesion and alignment behavior of human dermal fibroblasts
The aim of this study was to fabricate a submicro- and micro-patterned fibronectin coated wafer for a cell culture, which allows the positions and dimensions of the attached cells to be controlled. A replica m...
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Article
The effect of a long-term cyclic strain on human dermal fibroblasts cultured in a bioreactor on chitosan-based scaffolds for the development of tissue engineered artificial dermis
Mechanical stimulation is known to activate several cellular signal transduction pathways, leading to the induction of signaling molecules and extracellular matrix (ECM) proteins, thereby modulating cellular a...
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Article
Improvement of the biocompatibility of chitosan dermal scaffold by rigorous dry heat treatment
We have developed a rigorous heat treatment method to improve the biocompatibility of chitosan as a tissue-engineered scaffold. The chitosan scaffold was prepared by the controlled freezing and lyophilizing me...
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Article
Reconstruction of basement membrane in skin equivalent; role of laminin-1
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Article
A synthesis of O-diethylaminoethyl chitosan and its binding ability of cholate and deoxycholate anion in vitro
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Article
Synthesis of chitosan derivatives with quaternary ammonium salt and their antibacterial activity
N-alkyl chitosan derivatives were prepared by introducing alkyl groups into the amine groups of chitosan via Schiff’s base intermediates. Quaternization of the N-alkyl chitosan derivatives were c...
