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Synonymous mutations in representative yeast genes are mostly strongly non-neutral

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  1. Article

    Open Access

    Data-driven prediction on critical mechanical properties of engineered cementitious composites based on machine learning

    The present study introduces a novel approach utilizing machine learning techniques to predict the crucial mechanical properties of engineered cementitious composites (ECCs), spanning from typical to exception...

    Shuangquan Qing, Chuanxi Li in Scientific Reports (2024)

  2. Article

    Open Access

    The association between the change in severity score from baseline and the outcomes of critically ill patients was enhanced by integration of bioimpedance analysis parameters

    The study of the outcomes of critically ill patients has been a hard stuff in the field of intensive care. To explore the relationship between changes of severity scores, bioelectrical impedance analysis (BIA)...

    Zhen Hu, Chuan Li, Shuhua Zhu, Yongchun Ge, Dehua Gong in Scientific Reports (2024)

  3. Article

    Open Access

    Divergent and gram-scale syntheses of (–)-veratramine and (–)-cyclopamine

    Veratramine and cyclopamine, two of the most representative members of the isosteroidal alkaloids, are valuable molecules in agricultural and medicinal chemistry. While plant extraction of these compounds suff...

    Wenlong Hou, Hao Lin, Yanru Wu, Chuang Li, Jiajun Chen in Nature Communications (2024)

  4. Article

    Open Access

    Author Correction: Histone H2A monoubiquitination marks are targeted to specific sites by cohesin subunits in Arabidopsis

    Yu Zhang, Min Ma, Meng Liu, Aiqing Sun, **aoyun Zheng, Kunpeng Liu in Nature Communications (2024)

  5. Article

    Open Access

    Chromosome-level genome assembly of Solanum pimpinellifolium

    Solanum pimpinellifolium, the closest wild relative of the domesticated tomato, has high potential for use in breeding programs aimed at develo** multi-pathogen resistance and quality improvement. We generated ...

    Hongyu Han, **uhong Li, Tianze Li, Qian Chen, Jiuhai Zhao, Huawei Zhai in Scientific Data (2024)

  6. Article

    Open Access

    Analysis of vertical differentiation of vegetation in Taishan World Heritage site based on cloud model

    While the forests on Mount Taishan are predominantly man-made, there is a notable vertical variation in vegetation. This study employs the method of cloud model, quantifying uncertainty (fuzziness and randomne...

    Zhe Wang, Fang Han, Chuanrong Li, Weixing Shen, Zhijun Yang, Kun Li in Scientific Reports (2024)

  7. Article

    Open Access

    De novo transcriptome assembly database for 100 tissues from each of seven species of domestic herbivore

    Domesticated herbivores are an important agricultural resource that play a critical role in global food security, particularly as they can adapt to varied environments, including marginal lands. An understandi...

    Yifan Wang, Yiming Huang, Yongkang Zhen, Jiasheng Wang, Limin Wang in Scientific Data (2024)

  8. Article

    Open Access

    The Shigella kinase effector OspG modulates host ubiquitin signaling to escape septin-cage entrapment

    Shigella flexneri is a Gram-negative bacterium causing severe bloody dysentery. Its pathogenesis is largely dictated by a plasmid-encoded type III secretion system (T3SS) and its associated effectors. Among these...

    Wei **an, Jiaqi Fu, Qinxin Zhang, Chuang Li, Yan-Bo Zhao in Nature Communications (2024)

  9. Article

    Open Access

    Economic policy uncertainty and cash dividend policy: evidence from China

    This paper investigates the impact of economic policy uncertainty (EPU) on the dividend policy of listed companies, alongside its underlying mechanisms. Based on a panel data compilation from 4421 Chinese list...

    Chuanzhen Li, Liang Zhao, Yiwen Zhang in Humanities and Social Sciences Communications (2024)

  10. Article

    Open Access

    Alfalfa xeno-miR159a regulates bovine mammary epithelial cell proliferation and milk protein synthesis by targeting PTPRF

    Milk protein content is an important index to evaluate the quality and nutrition of milk. Accumulating evidence suggests that microRNAs (miRNAs) play important roles in bovine lactation, but little is known re...

    Hongjuan Duan, Shao** Li, Chuangwei Li, Lan Tian, Yun Ma in Scientific Reports (2024)

  11. Article

    Open Access

    Legionella metaeffector MavL reverses ubiquitin ADP-ribosylation via a conserved arginine-specific macrodomain

    ADP-ribosylation is a reversible post-translational modification involved in various cellular activities. Removal of ADP-ribosylation requires (ADP-ribosyl)hydrolases, with macrodomain enzymes being a major fa...

    Zhengrui Zhang, Jiaqi Fu, Johannes Gregor Matthias Rack, Chuang Li in Nature Communications (2024)

  12. Article

    Open Access

    Self-regulated reversal deformation and locomotion of structurally homogenous hydrogels subjected to constant light illumination

    Environmentally adaptive hydrogels that are capable of reconfiguration in response to external stimuli have shown great potential toward bioinspired actuation and soft robotics. Previous efforts have focused m...

    Kexin Guo, Xuehan Yang, Chao Zhou, Chuang Li in Nature Communications (2024)

  13. Article

    Open Access

    MRI can help differentiate Ménière’s disease from other menieriform diseases

    It is difficult to distinguish other pathologies mimicking Ménière’s disease (MD) clinically. This study aims to investigate the differences of imaging findings and features between MD and other menieriform di...

    **ye Li, Long Li, **anwen **, Na Hu, **ao Kong, Linsheng Wang in Scientific Reports (2023)

  14. Article

    Open Access

    Electrochemical nitrate reduction in acid enables high-efficiency ammonia synthesis and high-voltage pollutes-based fuel cells

    Most current research is devoted to electrochemical nitrate reduction reaction for ammonia synthesis under alkaline/neutral media while the investigation of nitrate reduction under acidic conditions is rarely ...

    Rong Zhang, Chuan Li, Huilin Cui, Yanbo Wang, Shaoce Zhang, Pei Li in Nature Communications (2023)

  15. Article

    Open Access

    Assessment of soil quality in an arid and barren mountainous of Shandong province, China

    Forest soils are important components of forest ecosystems, and soil quality assessment as a decision-making tool to understand forest soil quality and maintain soil productivity is essential. Various methods ...

    Lu Wang, Jianyao Guo, **umei Liu, Kun Li, Liang Ma, Yehan Tian in Scientific Reports (2023)

  16. Article

    Open Access

    MANF stimulates autophagy and restores mitochondrial homeostasis to treat autosomal dominant tubulointerstitial kidney disease in mice

    Misfolded protein aggregates may cause toxic proteinopathy, including autosomal dominant tubulointerstitial kidney disease due to uromodulin mutations (ADTKD-UMOD), a leading hereditary kidney disease. There are ...

    Yeawon Kim, Chuang Li, Chenjian Gu, Yili Fang, Eric Tycksen in Nature Communications (2023)

  17. Article

    Open Access

    SUN1/2 controls macrophage polarization via modulating nuclear size and stiffness

    Alteration of the size and stiffness of the nucleus triggered by environmental cues are thought to be important for eukaryotic cell fate and function. However, it remains unclear how context-dependent nuclear ...

    Shi Jiao, Chuanchuan Li, Fenghua Guo, **** Zhang, Hui Zhang in Nature Communications (2023)

  18. Article

    Open Access

    Broad and colossal edge supercurrent in Dirac semimetal Cd3As2 Josephson junctions

    Edge supercurrent has attracted great interest recently due to its crucial role in achieving and manipulating topological superconducting states. Proximity-induced superconductivity has been realized in quantu...

    Chun-Guang Chu, **g-**g Chen, An-Qi Wang, Zhen-Bing Tan in Nature Communications (2023)

  19. Article

    Open Access

    An application of stereo matching algorithm based on transfer learning on robots in multiple scenes

    Robot vision technology based on binocular vision holds tremendous potential for development in various fields, including 3D scene reconstruction, target detection, and autonomous driving. However, current bin...

    Yuanwei Bi, Chuanbiao Li, **angrong Tong, Guohui Wang, Haiwei Sun in Scientific Reports (2023)

  20. Article

    Open Access

    Pan-KRAS inhibitor disables oncogenic signalling and tumour growth

    KRAS is one of the most commonly mutated proteins in cancer, and efforts to directly inhibit its function have been continuing for decades. The most successful of these has been the development of covalent all...

    Dongsung Kim, Lorenz Herdeis, Dorothea Rudolph, Yulei Zhao, Jark Böttcher in Nature (2023)

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